Atrial Fibrillation
April 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Atrial Fibrillation abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Atrial Fibrillation. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Atrial Fibrillation. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Atrial Fibrillation every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation.
Authors:Lau WC, Chan EW, Cheung CL, Sing CW, Man KK, Lip GY, Siu CW, Lam JK, Lee AC, Wong IC
Institution:Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. University of Hong Kong, Hong Kong SAR, China. University of Hong Kong, Hong Kong SAR, China2Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. University of Hong Kong, Hong Kong SAR, China. University of Hong Kong, Hong Kong SAR, China3Department of Pediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. Birmingham, United Kingdom5Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. of Hong Kong, Hong Kong SAR, China. of Hong Kong, Hong Kong SAR, China. of Hong Kong, Hong Kong SAR, China. University of Hong Kong, Hong Kong SAR, China8Research Department of Practice and Policy, UCL School of Pharmacy, London, United Kingdom.
Journal:JAMA. 2017 Mar 21;317(11):1151-1158. doi: 10.1001/jama.2017.1363.

2:Adjunctive ablation strategies improve the efficacy of pulmonary vein isolation in non-paroxysmal atrial fibrillation: a systematic review and meta-analysis.
Authors:Afzal MR, Samanta A, Chatta J, Ansari B, Atherton S, Sabzwari S, Turagam M, Lakkireddy D, Houmsse M
Institution:a Division of Cardiovascular Medicine, Department of Internal Medicine, Electrophysiology Section, Ross Heart Hospital , The Wexner Medical Center at the Ohio State University Medical Center , Columbus , OH , USA. Kansas City , KS , USA. Kansas City , KS , USA. Kansas City , KS , USA. Kansas City , KS , USA. Kansas City , KS , USA. Kansas City , KS , USA. Kansas City , KS , USA. Electrophysiology Section, Ross Heart Hospital , The Wexner Medical Center at the Ohio State University Medical Center , Columbus , OH , USA.
Journal:Expert Rev Cardiovasc Ther. 2017 Mar;15(3):227-235. doi: 10.1080/14779072.2017.1294064. Epub 2017 Mar 1.

3:Association between statin use and ischemic stroke or major hemorrhage in patients taking dabigatran for atrial fibrillation.
Authors:Antoniou T, Macdonald EM, Yao Z, Hollands S, Gomes T, Tadrous M, Mamdani MM, Juurlink DN
Institution:Department of Family and Community Medicine (Antoniou), St. Michael's Hospital and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. tantoniou@smh.ca. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont. and University of Toronto; Li Ka Shing Knowledge Institute (Gomes) and Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Leslie Dan Faculty of Pharmacy (Gomes, Tadrous, Mamdani) and Department of Medicine (Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (Antoniou, Macdonald, Yao, Hollands, Gomes, Tadrous, Mamdani, Juurlink); Applied Health Research Centre (Tadrous), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.
Journal:CMAJ. 2017 Jan 9;189(1):E4-E10. doi: 10.1503/cmaj.160303. Epub 2016 Nov 21.

4:Screening for Obstructive Sleep Apnea in Patients with Atrial Fibrillation.
Authors:Genta PR, Drager LF, Lorenzi Filho G
Institution:Pulmonary Division, Heart Institute (InCor), Hospital das Clinicas, University of Sao Paulo School of Medicine, Av Dr. Eneas de Carvalho Aguiar, 44, 8th Floor, Sao Paulo, Sao Paulo 05403-000, Brasil. Clinicas, University of Sao Paulo School of Medicine, Av Dr. Eneas de Carvalho Aguiar, 44, 8th Floor, Sao Paulo, Sao Paulo 05403-000, Brasil. Sao Paulo School of Medicine, Av Dr. Eneas de Carvalho Aguiar, 44, 8th Floor, Sao Paulo, Sao Paulo 05403-000, Brasil. Electronic address: geraldo.lorenzi@gmail.com.
Journal:Sleep Med Clin. 2017 Mar;12(1):99-105. doi: 10.1016/j.jsmc.2016.10.009. Epub 2016 Dec 20.

5:Effect of statin use on clinical outcomes in ischemic stroke patients with atrial fibrillation.
Authors:Wu YL, Saver JL, Chen PC, Lee JD, Wang HH, Rao NM, Lee M, Ovbiagele B
Institution:aDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Chiayi Branch bDepartment of Public Health, China Medical University, Taichung, Taiwan cStroke Center, Geffen School of Medicine, University of California, Los Angeles, CA dDepartment of Healthcare Management, Chang Gung University, Taoyuan, Taiwan eDepartment of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, SC.
Journal:Medicine (Baltimore). 2017 Feb;96(5):e5918. doi: 10.1097/MD.0000000000005918.

6:Management strategies for atrial fibrillation.
Authors:Patel PA, Ali N, Hogarth A, Tayebjee MH
Institution:1 Department of Cardiology, Leeds General Infirmary, Leeds LS1 3EX, UK.
Journal:J R Soc Med. 2017 Jan;110(1):13-22. doi: 10.1177/0141076816677857.

7:Anticoagulation in patients at high risk of stroke without documented atrial fibrillation. Time for a paradigm shift?
Authors:Bayes de Luna A, Baranchuk A, Martinez-Selles M, Platonov PG
Institution:Catalan Institute of Cardiovascular Sciences, St. Pau Hospital, Barcelona, Spain. ON, Canada. Europea, Universidad Complutense, Madrid, Spain. Arrhythmia Clinic Sweden, Skane University Hospital, Lund, Sweden.
Journal:Ann Noninvasive Electrocardiol. 2017 Jan;22(1). doi: 10.1111/anec.12417. Epub 2016 Dec 16.

8:Comparing the clinical outcomes in patients with atrial fibrillation receiving dual antiplatelet therapy and patients receiving an addition of an anticoagulant after coronary stent implantation: A systematic review and meta-analysis of observational studies.
Authors:Chaudhary N, Bundhun PK, Yan H
Institution:Department of Geriatric Cardiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China.
Journal:Medicine (Baltimore). 2016 Dec;95(50):e5581.

9:Direct oral anticoagulants and cardiovascular prevention in patients with nonvalvular atrial fibrillation.
Authors:Marin F, Anguita-Sanchez M, Sanmartin M
Institution:a Department of Cardiology , Hospital Universitario Virgen de la Arrixaca, IMIB-Arrixaca , Murcia , Spain. Spain.
Journal:Expert Opin Pharmacother. 2017 Jan;18(1):67-77. doi: 10.1080/14656566.2016.1267140. Epub 2016 Dec 15.

10:How to Improve Cardiac Resynchronization Therapy Benefit in Atrial Fibrillation Patients: Pulmonary Vein Isolation (and Beyond).
Authors:Gianni C, Di Biase L, Mohanty S, Gokoglan Y, Gunes MF, Al-Ahmad A, Burkhardt JD, Natale A
Institution:Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 North IH-35, Suite 700, Austin, TX 78705, USA; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Suite 700, Austin, TX 78705, USA; Arrhythmia Services, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA; Department of Biomedical Engineering, University of Texas, Austin, TX, USA; Department of Cardiology, University of Foggia, Foggia, Italy. Suite 700, Austin, TX 78705, USA. Suite 700, Austin, TX 78705, USA. Suite 700, Austin, TX 78705, USA. Suite 700, Austin, TX 78705, USA. Suite 700, Austin, TX 78705, USA. Suite 700, Austin, TX 78705, USA; MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Division of Cardiology, Stanford University, Stanford, CA, USA; Electrophysiology and Arrhythmia Services, California Pacific Medical Center, San Francisco, CA, USA; Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, CA, USA; Dell Medical School, University of Texas, Austin, TX, USA. Electronic address: dr.natale@gmail.com.
Journal:Heart Fail Clin. 2017 Jan;13(1):199-208. doi: 10.1016/j.hfc.2016.07.016.

11:Atrioventricular Node Ablation.
Authors:Gasparini M
Institution:EP and Pacing Unit, Humanitas Research Hospital, 20089 Rozzano-Milano, Italy. Electronic address: maurizio.gasparini@humanitas.it.
Journal:Heart Fail Clin. 2017 Jan;13(1):193-198. doi: 10.1016/j.hfc.2016.07.015.

12:Atrial Fibrillation During Cardiac Resynchronization Therapy.
Authors:Kloosterman M, Maass AH, Rienstra M, Van Gelder IC
Institution:Department of Cardiology, Thoraxcenter, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands. Box 30.001, 9700 RB Groningen, The Netherlands. Box 30.001, 9700 RB Groningen, The Netherlands. Box 30.001, 9700 RB Groningen, The Netherlands. Electronic address: i.c.van.gelder@umcg.nl.
Journal:Heart Fail Clin. 2017 Jan;13(1):179-192. doi: 10.1016/j.hfc.2016.07.014.

13:Association between antithrombotic treatment and hemorrhagic stroke in patients with atrial fibrillation-a cohort study in primary care.
Authors:Wandell P, Carlsson AC, Holzmann M, Arnlov J, Johansson SE, Sundquist J, Sundquist K
Institution:Division of Family Medicine, Department of Neurobiology, Care Science and Society, Karolinska Institutet, Alfred Nobels Alle 12, 141 83, Huddinge, Sweden. per.wandell@ki.se. Society, Karolinska Institutet, Alfred Nobels Alle 12, 141 83, Huddinge, Sweden. Uppsala, Sweden. Sweden. Uppsala, Sweden.
Journal:Eur J Clin Pharmacol. 2017 Feb;73(2):215-221. doi: 10.1007/s00228-016-2152-8. Epub 2016 Nov 8.

14:Sudden death and its risk factors after atrioventricular junction ablation and pacemaker implantation in patients with atrial fibrillation.
Authors:Wang RX, Lee HC, Li JP, Hodge DO, Cha YM, Friedman PA, Munger TM, Srivathsan K, Pavri BB, Shen WK
Institution:Department of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, PR China. Informatics, Mayo Clinic, Rochester, Minnesota. University, Wuxi 214023, PR China. Informatics, Mayo Clinic, Rochester, Minnesota. Informatics, Mayo Clinic, Rochester, Minnesota. Informatics, Mayo Clinic, Rochester, Minnesota. Informatics, Mayo Clinic, Rochester, Minnesota. Pennsylvania.
Journal:Clin Cardiol. 2017 Jan;40(1):18-25. doi: 10.1002/clc.22600. Epub 2016 Oct 17.

15:New Oral Anticoagulants in Nonvalvular Atrial Fibrillation.
Authors:Urooj F, Kulkarni A, Stapleton D, Kaluski E
Institution:Department of Internal Medicine, Cardiology Hospitalist Team, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Journal:Clin Cardiol. 2016 Dec;39(12):739-746. doi: 10.1002/clc.22582. Epub 2016 Oct 7.

16:Effect of restoring sinus rhythm in hypertensive patients with atrial fibrillation undergoing electrical cardioversion.
Authors:Maselli M, Giantin V, Franchin A, Attanasio F, Tramontano A, De Toni P, Pengo V, Corrado D, Manzato E
Institution:aGeriatric Unit, Department of Medicine bCardiology Division, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua cCNR - Neuroscience Institute, Padua, Italy.
Journal:Blood Press Monit. 2016 Dec;21(6):335-339.

17:Pulmonary Hypertension due to Radiofrequency Catheter Ablation (RFCA) for Atrial Fibrillation: The Lungs, the Atrium or the Ventricle?
Authors:Verma I, Tripathi H, Sikachi RR, Agrawal A
Institution:Department of Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA. USA. Northwell Health - Hofstra Northwell School of Medicine Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, New York, USA. Electronic address: abhinav72@gmail.com.
Journal:Heart Lung Circ. 2016 Dec;25(12):1177-1183. doi: 10.1016/j.hlc.2016.05.125. Epub 2016 Jul 18.

18:Practical Considerations for the Use of Direct Oral Anticoagulants in Patients With Atrial Fibrillation.
Authors:Stacy Z, Richter S
Institution:St Louis College of Pharmacy, St Louis, MO, USA zachary.stacy@stlcop.edu.
Journal:Clin Appl Thromb Hemost. 2017 Jan;23(1):5-19. Epub 2016 Mar 17.

For a FREE PREVIEW of the Medifocus Guidebook on Atrial Fibrillation click here

To purchase a copy of the COMPLETE Medifocus Guidebook on Atrial Fibrillation click here

To subscribe to additional FREE Medifocus Digest Alert on other disease/condition areas click here

  
Get the Medifocus Guidebook on Atrial Fibrillation...
at a Special 20% Discount


Medifocus Guidebook on Atrial Fibrillation

Updated: January 22, 2017
168 Pages

This one of a kind Guidebook offers:

  • Answers to your critical health questions including the latest treatments, clinical trials, and expert research.
     
  • High Quality, Professional level information you can trust and understand culled from the latest peer-reviewed journals.
     
  • Timely, up to date content with free guidebook updates for 1 year.
     
  • A unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks.
     
  • Over 130,000 Guidebooks Sold
     
  • 100% Risk Free Money Back Guarantee



ORDER THE GUIDEBOOK

The Medifocus Guidebook on Atrial Fibrillation is available in the following two convenient formats:

PRINTED GUIDEBOOK

Soft-cover book that is available for immediate shipping via either U.S. Priority Mail or International AirMail (outside the U.S.).

  • Regular List Price = $36.95
  • Less 20% Discount = - $7.40
  • Discounted Price = $29.55(excluding shipping & handling)

Order the Printed Guidebook

DIGITAL GUIDEBOOK

Available for immediate download as a PDF document.

  • Regular List Price = $27.95
  • Less 20% Discount = - $5.60
  • Discounted Price = $22.35

Order the Digital Guidebook



Order by Phone

Call Toll Free in the U.S.
1-800-965-3002

From Outside the U.S.
1-301-649-9300

You can also receive a 20% discount when you order your Guidebook by phone.

To receive your 20% discount, simply mention the Discount Coupon Code below to the customer service representative taking your order.

Discount Coupon Code for
Phone Orders

AF72405795

Coupon Expires: May 26, 2017



What Our Customers Are Saying...

"The MediFocus Guidebook on Atrial Fibrillation has enhanced and clearly explained this condition for me. It has also enabled me to make choices with confidence regarding my treatment. The references in the medical literature section has put me in touch with the research base in this country. Many thanks."
E.B.
Seaford, East Sussex


"I found the MediFocus Guidebook on Atrial Fibrillation extremely informative and very easy to understand. As a result of the information in the Guidebook, I'm able to discuss my problem with my doctor in a more informed manner and make better decisions regarding treatment."
J.T.F.
Agoura Hills, California


"The Medifocus Guidebook on Atrial Fibrillation gave me far more information than was available from my doctor and helped me understand my condition."
C.B.
Rancho Santa Fe, California



  
Medifocus Digest Alert is published monthly by Medifocus, Inc.
6810 Park Heights Avenue, Suite C5, Baltimore, MD 21215 USA
Copyright © 2013 Medifocus, Inc. All rights reserved.