| | Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.
Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Atrial Fibrillation abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Atrial Fibrillation. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Atrial Fibrillation. You can access the summaries of each article referenced below by simply clicking on the article Title.
We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Atrial Fibrillation every 3 months. Thank you for your ongoing subscription to this publication.
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.
| Authors: | Yu YB, Liu J, Fu GH, Fang RY, Gao F, Chu HM |
| Institution: | Arrhythmia Center, Ningbo First Hospital, Ningbo, Zhejiang, China. | | Journal: | Medicine (Baltimore). 2018 Nov;97(46):e12841. doi: 10.1097/MD.0000000000012841. |
| Authors: | Bhatia HS, Hsu JC, Kim RJ |
| Institution: | Department of Medicine, Weill Cornell Medicine, New York, New York. Diego, California. Diego, California. New York. | | Journal: | Clin Cardiol. 2018 Oct;41(10):1395-1402. doi: 10.1002/clc.23085. Epub 2018 Oct 25. |
| Authors: | Clarke A, Ibrahim A, Kiernan TJ |
| Institution: | a University of Limerick, Graduate Entry Medical School (GEMS) , Castletroy , Ireland. | | Journal: | Expert Rev Cardiovasc Ther. 2018 Oct;16(10):715-723. doi: 10.1080/14779072.2018.1521721. Epub 2018 Sep 20. |
| Authors: | Gomez-Outes A, Suarez-Gea ML, Garcia-Pinilla JM |
| Institution: | a Division of Pharmacology and Clinical Drug Evaluation, Medicines for Human Use , Spanish Agency for Medicines and Medical Devices (AEMPS) , Madrid , Spain. , Spanish Agency for Medicines and Medical Devices (AEMPS) , Madrid , Spain. Malaga (IBIMA), Hospital Universitario Virgen de la Victoria , Malaga , Spain. de Salud Carlos III , Madrid , Spain. | | Journal: | Expert Opin Pharmacother. 2018 Sep;19(13):1427-1440. doi: 10.1080/14656566.2018.1511703. Epub 2018 Sep 8. |
| Authors: | Diener HC, Ntaios G, O'Donnell M, Easton JD |
| Institution: | a Department of Neurology , University Hospital Essen , Essen , Germany. Sciences , Galway , Ireland. Francisco , CA , USA. | | Journal: | Expert Opin Pharmacother. 2018 Oct;19(14):1597-1602. doi: 10.1080/14656566.2018.1515913. Epub 2018 Sep 17. |
| Authors: | Walsh K, Marchlinski F |
| Institution: | a Cardiac Electrophysiology Section, Cardiovascular Division , Hospital of University of Pennsylvania , Philadelphia , PA , USA. University of Pennsylvania , Philadelphia , PA , USA. | | Journal: | Expert Rev Cardiovasc Ther. 2018 Sep;16(9):679-692. doi: 10.1080/14779072.2018.1510317. Epub 2018 Aug 28. |
| Authors: | Stacy ZA, Richter SK |
| Institution: | Division of Acute Care Pharmacy, Pharmacy Practice Department, St Louis College of Pharmacy, 4588 Parkview Place, St Louis, MO 63110-1088, USA. of Pharmacy, St Louis, MO, USA. | | Journal: | Ther Adv Cardiovasc Dis. 2018 Sep;12(9):247-262. doi: 10.1177/1753944718787384. |
| Authors: | Gourraud JB, Khairy P, Abadir S, Tadros R, Cadrin-Tourigny J, Macle L, Dyrda K, Mondesert B, Dubuc M, Guerra PG, Thibault B, Roy D, Talajic M, Rivard L |
| Institution: | a Electrophysiology Service , Montreal Heart Institute, Universite de Montreal , Montreal , Canada.; b Department of Pediatric Cardiology , Sainte-Justine Hospital, Universite de Montreal , Montreal Canada. | | Journal: | Expert Rev Cardiovasc Ther. 2018 Jul;16(7):489-500. doi: 10.1080/14779072.2018.1490644. Epub 2018 Jul 2. |
| Authors: | Li H, Lin X, Ma X, Tao J, Zou R, Yang S, Liu H, Hua P |
| Institution: | Department of Cardiovascular Surgery, Quanzhou First Hospital of Fujian Medical University, Quanzhou 362000, China. University, Guangzhou 510120, China. University, Guangzhou 510120, China. University, Guangzhou 510120, China. | | Journal: | Biomed Res Int. 2018 Apr 29;2018:3651212. doi: 10.1155/2018/3651212. eCollection 2018. |
| Authors: | Rogers PA, Bernard ML, Madias C, Thihalolipavan S, Mark Estes NA 3rd, Morin DP |
| Journal: | Curr Probl Cardiol. 2018 Jun;43(6):241-283. doi: 10.1016/j.cpcardiol.2017.06.001. Epub 2017 Jun 7. |
| Authors: | Khattak F, Alam MB, Paul TK, Rijal S, Wazir S, Lavie CJ, Saba S |
| Institution: | Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address: fhk2@pitt.edu. Virginia. Illinois. Pittsburgh, Pennsylvania. Queensland School of Medicine, New Orleans, Louisiana, Louisiana. Pittsburgh, Pennsylvania. | | Journal: | Am J Med Sci. 2018 May;355(5):467-476. doi: 10.1016/j.amjms.2018.01.013. Epub 2018 Jan 31. |
| Authors: | Staerk L, Wang B, Preis SR, Larson MG, Lubitz SA, Ellinor PT, McManus DD, Ko D, Weng LC, Lunetta KL, Frost L, Benjamin EJ, Trinquart L |
| Institution: | National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, USA.; Department of Cardiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark.; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, USA. | | Journal: | BMJ. 2018 Apr 26;361:k1453. doi: 10.1136/bmj.k1453. |
| Authors: | Zhang XY, Yu RH, Dong JZ |
| Institution: | Emergency Center, Capital Medical University affiliated Beijing Anzhen Hospital, Beijing, China. Electronic address: xinyongzhangdoc@163.com. Hospital, Beijing, China. Hospital, Beijing, China. | | Journal: | Am J Med Sci. 2018 Apr;355(4):357-361. doi: 10.1016/j.amjms.2017.12.002. Epub 2017 Dec 9. |
| Authors: | Li Y, Pastori D, Guo Y, Wang Y, Lip GYH |
| Institution: | Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom; Chinese PLA General Hospital, Chinese PLA Medical School, Department of Cardiology, Beijing, China. United Kingdom; I Clinica Medica, Atherothrombosis Center, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy. Cardiology, Beijing, China. Cardiology, Beijing, China. United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address: g.y.h.lip@bham.ac.uk. | | Journal: | Int J Cardiol. 2018 Jun 15;261:92-98. doi: 10.1016/j.ijcard.2018.02.051. |
| Authors: | Mene-Afejuku TO, Lopez PD, Akinlonu A, Dumancas C, Visco F, Mushiyev S, Pekler G |
| Institution: | Department of Medicine, Health + Hospitals/Metropolitan, New York, NY, USA. persiod.lopez@gmail.com. New York, NY, USA. New York, NY, USA. New York, NY, USA. | | Journal: | Am J Cardiovasc Drugs. 2018 Oct;18(5):347-360. doi: 10.1007/s40256-018-0276-1. |
| Authors: | Zhao E, Chen S, Du Y, Zhang Y |
| Institution: | Department of Structural Heart Disease, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. | | Journal: | Biomed Res Int. 2018 Jan 18;2018:5215868. doi: 10.1155/2018/5215868. eCollection 2018. |
| Authors: | Proietti M, Romiti GF, Romanazzi I, Farcomeni A, Staerk L, Nielsen PB, Lip GYH |
| Institution: | Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom; IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Department of Neuroscience, Milan, Italy. Rome, Italy. Hellerup, Denmark. Health, Aalborg University, Aalborg, Denmark. Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Aalborg, Denmark. Electronic address: g.y.h.lip@bham.ac.uk. | | Journal: | Int J Cardiol. 2018 Jun 15;261:84-91. doi: 10.1016/j.ijcard.2018.03.053. Epub 2018 Mar 14. |
| Authors: | Murray MI, Arnold A, Younis M, Varghese S, Zeiher AM |
| Institution: | Department of Cardiology, University Hospital Frankfurt, Frankfurt-am Main, Germany. marieisabel.murray@gmail.com. London, UK. marieisabel.murray@gmail.com. London, UK. College London, London, UK. London, UK. London, UK. Germany. | | Journal: | Clin Res Cardiol. 2018 Aug;107(8):658-669. doi: 10.1007/s00392-018-1232-4. Epub 2018 Mar 21. |
| Authors: | Chen C, Zhou X, Zhu M, Chen S, Chen J, Cai H, Dai J, Xu X, Mao W |
| Institution: | Department of Cardiology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. maoweilw@163.com.; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China. | | Journal: | J Interv Card Electrophysiol. 2018 Jun;52(1):9-18. doi: 10.1007/s10840-018-0349-8. Epub 2018 Mar 16. |
| Authors: | Capucci A, Cipolletta L, Guerra F, Giannini I |
| Institution: | a Department of Scienze Cardiovascolari , Clinica di Cardiologia Universita' Politecnica delle Marche - Scienze Cardiovascolari , Ancona , Italy. | | Journal: | Expert Opin Emerg Drugs. 2018 Mar;23(1):25-36. doi: 10.1080/14728214.2018.1446941. Epub 2018 Mar 13. |
| Authors: | Dalmau Llorca MR, Goncalves AQ, Forcadell Drago E, Fernandez-Saez J, Hernandez Rojas Z, Pepio Vilaubi JM, Rodriguez Cumplido D, Morral Parente RM, Aguilar Martin C |
| Institution: | Equip d'Atencio Primaria Tortosa Oest, Institut Catala de la Salut. d'Investigacio en Atencio Primaria (IDIAP) Jordi Gol. d'Investigacio en Atencio Primaria (IDIAP) Jordi Gol. Institut Catala de la Salut, Tortosa. d'Investigacio en Atencio Primaria (IDIAP) Jordi Gol. d'Investigacio en Atencio Primaria (IDIAP) Jordi Gol. de la Salut, Tortosa, Tarragona, Spain. | | Journal: | Medicine (Baltimore). 2018 Jan;97(3):e9578. doi: 10.1097/MD.0000000000009578. |
| Authors: | Kumar S, de Lusignan S, McGovern A, Correa A, Hriskova M, Gatenby P, Jones S, Goldsmith D, Camm AJ |
| Institution: | Centre for Medical Imaging, University College London, London, UK. Guildford, UK. Guildford, UK. Guildford, UK. UK. Guildford, UK. UK. Guildford, UK. Guildford, UK. School of Medicine, New York, USA. London, UK. Foundation Trust, London, UK. London, UK jcamm@sgul.ac.uk. | | Journal: | BMJ. 2018 Feb 14;360:k342. doi: 10.1136/bmj.k342. |
| Authors: | Mohanty S, Trivedi C, Gianni C, Natale A |
| Institution: | a Texas Cardiac Arrhythmia Institute , St. David's Medical Center , Austin , TX , USA. USA. USA. USA. San Francisco , CA , USA. Medicine , Cleveland , OH , USA. | | Journal: | Expert Opin Pharmacother. 2018 Mar;19(4):365-374. doi: 10.1080/14656566.2018.1434144. Epub 2018 Feb 9. |
| Authors: | Marrouche NF, Brachmann J, Andresen D, Siebels J, Boersma L, Jordaens L, Merkely B, Pokushalov E, Sanders P, Proff J, Schunkert H, Christ H, Vogt J, Bansch D |
| Institution: | From the Comprehensive Arrhythmia Research and Management Center, Division of Cardiovascular Medicine, School of Medicine, University of Utah Health, Salt Lake City (N.F.M.); Klinikum Coburg, Coburg (J.B.), Kardiologie an den Ev. Elisabeth-Kliniken (D.A.) and Biotronik (J.P., H.S.), Berlin, Klinik Rotes Kreuz, Frankfurt/Main (J.S.), Klinikum Links der Weser, Bremen (L.B.), Deutsches Herzzentrum Munchen, Munich (H.C.), Institute of Medical Statistics and Computational Biology, Cologne (D.B.), and KMG Klinikum, Gustrow (J.V.) - all in Germany; Antonius Ziekenhuis Nieuwegein, Nieuwegein (L.J.), and the Erasmus University Medical Center, Rotterdam (B.M.) - both in the Netherlands; Semmelweis Medical University, Budapest, Hungary (E.P.); and the State Research Institute of Circulation Pathology, Novosibirsk, Russia (P.S.). | | Journal: | N Engl J Med. 2018 Feb 1;378(5):417-427. doi: 10.1056/NEJMoa1707855. |
| Authors: | Effron MB, Gibson CM |
| Institution: | Division of Consultative Cardiology, John Ochsner Heart and Vascular Institute, New Orleans, LA, United States. Electronic address: mark.effron@ochsner.org. Deaconess Medical Center, Harvard Medical School, Boston, MA, United States. | | Journal: | Prog Cardiovasc Dis. 2018 Jan - Feb;60(4-5):531-536. doi: 10.1016/j.pcad.2018.01.010. Epub 2018 Jan 31. |
| Authors: | Chen ST, Patel MR |
| Institution: | Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, NC, United States; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, United States. Medicine, Durham, NC, United States; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, United States. Electronic address: manesh.patel@duke.edu. | | Journal: | Prog Cardiovasc Dis. 2018 Jan - Feb;60(4-5):514-523. doi: 10.1016/j.pcad.2018.01.005. Epub 2018 Jan 13. |
| Authors: | Price MJ |
| Institution: | Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, CA, United States. Electronic address: price.matthew@scrippshealth.org. | | Journal: | Prog Cardiovasc Dis. 2018 Jan - Feb;60(4-5):542-549. doi: 10.1016/j.pcad.2018.01.002. Epub 2018 Jan 12. |
| Authors: | Larsson SC, Drca N, Jensen-Urstad M, Wolk A |
| Institution: | Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: susanna.larsson@ki.se. Stockholm, Sweden. Stockholm, Sweden. Institutet, Stockholm, Sweden; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. | | Journal: | Am Heart J. 2018 Jan;195:86-90. doi: 10.1016/j.ahj.2017.09.013. Epub 2017 Sep 21. |
| Authors: | Hussain N, Gersh BJ, Gonzalez Carta K, Sydo N, Lopez-Jimenez F, Kopecky SL, Thomas RJ, Asirvatham SJ, Allison TG |
| Institution: | Mayo Clinic, Rochester, Minnesota. University, Budapest, Hungary. | | Journal: | Am J Cardiol. 2018 Jan 1;121(1):41-49. doi: 10.1016/j.amjcard.2017.09.021. Epub 2017 Nov 13. |
| Authors: | Proietti M, Romanazzi I, Romiti GF, Farcomeni A, Lip GYH |
| Institution: | From the Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom (M.P., I.R., G.F.R., G.Y.H.L.); Department of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy (M.P.); Department of Public Health and Infectious Disease, Sapienza-University of Rome, Italy (A.F.); and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health, Aalborg University, Denmark (G.Y.H.L.). g.y.h.lip@bham.ac.uk. | | Journal: | Stroke. 2018 Jan;49(1):98-106. doi: 10.1161/STROKEAHA.117.018395. Epub 2017 Nov 22. |
| Authors: | Hong KL, Glover BM |
| Institution: | Department of Cardiology, Queen's University, Kingston, Ontario, Canada. | | Journal: | Curr Opin Cardiol. 2018 Jan;33(1):14-19. doi: 10.1097/HCO.0000000000000470. |
| Authors: | Gasparini M, Galimberti P |
| Institution: | Electrophysiology and Pacing Unit, Humanitas Research Hospital, Rozzano, Milano, Italy. | | Journal: | Curr Opin Cardiol. 2018 Jan;33(1):1-6. doi: 10.1097/HCO.0000000000000472. |
| Authors: | Kwon Y, Koene RJ, Johnson AR, Lin GM, Ferguson JD |
| Institution: | Division of Cardiovascular Medicine, Department of Medicine and Department of Sleep Medicine, University of Virginia, Charlottesville, VA, USA. Electronic address: yk2j@hscmail.mcc.virginia.edu. Clinic Foundation, Cleveland, OH, USA. Sleep Medicine, University of Virginia, Charlottesville, VA, USA. Taiwan; Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan; College of Science and Engineering, National Dong Hwa University, Hualien 974, Taiwan. Sleep Medicine, University of Virginia, Charlottesville, VA, USA. | | Journal: | Sleep Med Rev. 2018 Jun;39:134-142. doi: 10.1016/j.smrv.2017.08.005. Epub 2017 Sep 4. |
| Authors: | Bai Y, Guo SD, Deng H, Shantsila A, Fauchier L, Ma CS, Lip GYH |
| Institution: | Institute of Cardiovascular Sciences, University of Birmingham, Birmingham B18 7QH, UK. Beijing 100730, China. Hepingli, Chaoyang District, Beijing100029, China. of Medical Science, Guangzhou, China. 7QH, UK. Universitaire Trousseau et Faculte de Medecine, Universite Franis Rabelais, Tours, France. Beijing 100730, China. National Clinical Research Center for Cardiovascular Diseases, Beijing Shi, China. 7QH, UK. University, Aalborg, Denmark. | | Journal: | Age Ageing. 2018 Jan 1;47(1):9-17. doi: 10.1093/ageing/afx103. |
| Authors: | Michniewicz E, Mlodawska E, Lopatowska P, Tomaszuk-Kazberuk A, Malyszko J |
| Institution: | Department of Cardiology, Medical University in Bialystok, Bialystok, Poland. University, M. Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland. Electronic address: jolmal@poczta.onet.pl. | | Journal: | Adv Med Sci. 2018 Mar;63(1):30-35. doi: 10.1016/j.advms.2017.06.005. Epub 2017 Aug 14. |
| Authors: | Dietzel J, Haeusler KG, Endres M |
| Institution: | Center for Stroke Research Berlin, Charite - Universitatsmedizin Berlin, Germany. | | Journal: | Europace. 2018 Mar 1;20(3):408-419. doi: 10.1093/europace/eux031. |
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What Our Customers Are Saying... "The MediFocus Guidebook on Atrial Fibrillation has enhanced and clearly explained this condition for me. It has also enabled me to make choices with confidence regarding my treatment. The references in the medical literature section has put me in touch with the research base in this country. Many thanks."
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Seaford, East Sussex
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Agoura Hills, California
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