Chronic Pancreatitis
May 2020 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Chronic Pancreatitis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Chronic Pancreatitis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Chronic Pancreatitis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Chronic Pancreatitis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:ACG Clinical Guideline: Chronic Pancreatitis.
Authors:Gardner TB, Adler DG, Forsmark CE, Sauer BG, Taylor JR, Whitcomb DC
Institution:Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA. Lake City, Utah, USA. Gainesville, Florida, USA. Virginia, USA. Missouri, USA. Cell Biology and Molecular Physiology, and Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Journal:Am J Gastroenterol. 2020 Mar;115(3):322-339. doi: 10.14309/ajg.0000000000000535.

2:Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis: The ESCAPE Randomized Clinical Trial.
Authors:Issa Y, Kempeneers MA, Bruno MJ, Fockens P, Poley JW, Ahmed Ali U, Bollen TL, Busch OR, Dejong CH, van Duijvendijk P, van Dullemen HM, van Eijck CH, van Goor H, Hadithi M, Haveman JW, Keulemans Y, Nieuwenhuijs VB, Poen AC, Rauws EA, Tan AC, Thijs W, Timmer R, Witteman BJ, Besselink MG, van Hooft JE, van Santvoort HC, Dijkgraaf MG, Boermeester MA
Institution:Department of Surgery, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. University of Amsterdam, Amsterdam, the Netherlands. Center, Rotterdam, Amsterdam, the Netherlands. Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Center, Rotterdam, Amsterdam, the Netherlands. University of Amsterdam, Amsterdam, the Netherlands. University of Amsterdam, Amsterdam, the Netherlands. Netherlands. University of Groningen, Groningen, the Netherlands. Netherlands. Netherlands. Groningen, the Netherlands. the Netherlands. Netherlands. Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Nijmegen, the Netherlands. Netherlands. Netherlands. Netherlands. University of Amsterdam, Amsterdam, the Netherlands. Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Public Health, Amsterdam UMC, University of Amsterdam, the Netherlands. University of Amsterdam, Amsterdam, the Netherlands.
Journal:JAMA. 2020 Jan 21;323(3):237-247. doi: 10.1001/jama.2019.20967.

3:CT and MR features that can help to differentiate between focal chronic pancreatitis and pancreatic cancer.
Authors:Srisajjakul S, Prapaisilp P, Bangchokdee S
Institution:Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. tiam.mahidol@gmail.com. Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. Road, Muang District, Pathum Thani, 12000, Thailand.
Journal:Radiol Med. 2020 Apr;125(4):356-364. doi: 10.1007/s11547-019-01132-7. Epub 2020 Jan 13.

4:Case 273: Pancreatic Duct-to-Portal Vein Fistula with Secondary Portal Vein Pyophlebitis-A Rare Complication of Chronic Pancreatitis.
Authors:Aguilar HN, Manolea F, Patel VH, Low G
Institution:From the Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, 2A2.41 WMC, 8440-112 St, Edmonton, AB, Canada T6G 2B7. Hospital, 2A2.41 WMC, 8440-112 St, Edmonton, AB, Canada T6G 2B7. Hospital, 2A2.41 WMC, 8440-112 St, Edmonton, AB, Canada T6G 2B7. Hospital, 2A2.41 WMC, 8440-112 St, Edmonton, AB, Canada T6G 2B7.
Journal:Radiology. 2020 Jan;294(1):234-237. doi: 10.1148/radiol.2019171373.

5:Chronic Pancreatitis: Managing a Difficult Disease.
Authors:Hart PA, Conwell DL
Institution:Section of Pancreatic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA. Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Journal:Am J Gastroenterol. 2020 Jan;115(1):49-55. doi: 10.14309/ajg.0000000000000421.

6:The impact of surgical complications on the outcome of total pancreatectomy with islet autotransplantation.
Authors:Shahbazov R, Naziruddin B, Salam O, Saracino G, Levy MF, Beecherl E, Onaca N
Institution:Department of Surgery, Division of Transplantation, Upstate Medical University, 750 E. Adams Street, Syracuse, NY, 13210, USA. Electronic address: ShahbazR@upstate.edu. Suite 950, Dallas, TX, 75246, USA. Electronic address: bashoo.naziruddin@bswhealth.org. Dallas, TX, 75226, USA. Electronic address: osmaan.salam@gmail.com. Suite 950, Dallas, TX, 75246, USA. Electronic address: giovanna.saracino@bswhealth.org. Street, Richmond, VA, 23298, USA. Electronic address: marlon.levy@vcuhealth.org. Suite 950, Dallas, TX, 75246, USA. Electronic address: ernest.beecherl@bswhealth.org. Suite 950, Dallas, TX, 75246, USA. Electronic address: nicholas.onaca@bswhealth.org.
Journal:Am J Surg. 2020 Jan;219(1):99-105. doi: 10.1016/j.amjsurg.2019.04.007. Epub 2019 Apr 15.

7:Statins and pancreatic cancer risk in patients with chronic pancreatitis: A Danish nationwide population-based cohort study.
Authors:KirkegÄrd J, Lund JL, Mortensen FV, Cronin-Fenton D
Institution:Department of Surgery, Section for Hepato-Pancreato-Biliary Surgery, Aarhus University Hospital, Aarhus, Denmark. North Carolina at Chapel Hill, Chapel Hill, NC, USA. University Hospital, Aarhus, Denmark.
Journal:Int J Cancer. 2020 Feb 1;146(3):610-616. doi: 10.1002/ijc.32264. Epub 2019 Mar 28.

8:Positive predictive value of acute and chronic pancreatitis diagnoses in the Danish National Patient Registry: A validation study.
Authors:KirkegÄrd J, Mortensen MR, Johannsen IR, Mortensen FV, Cronin-Fenton D
Institution:Department of Surgery, Aarhus University Hospital, Denmark.
Journal:Scand J Public Health. 2020 Feb;48(1):14-19. doi: 10.1177/1403494818773535. Epub 2018 May 3.

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"Thank you. Thank you. Thank you. I am a 37-year old man with chronic pancreatitis. I didn't know where to start looking for information about this condition on the Internet. Medifocus gave me a great start. The explanations of my illness were very comprehensive and now I can talk better with my doctor about my treatment options."
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