Carcinoid Tumors
October 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Carcinoid Tumors abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Carcinoid Tumors. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Carcinoid Tumors. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Carcinoid Tumors every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Carcinoid heart disease.
Authors:Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW
Institution:Department of Cardiology, Division of Medicine, MD Anderson Cancer Center, Houston, Texas, USA.; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, Texas, USA.
Journal:Heart. 2017 Oct;103(19):1488-1495. doi: 10.1136/heartjnl-2017-311261. Epub 2017 Jun 8.

2:Appendiceal goblet cell carcinoid: common errors in staging and clinical interpretation with a proposal for an improved terminology.
Authors:Wen KW, Hale G, Shafizadeh N, Hosseini M, Huang A, Kakar S
Institution:Department of Pathology, University of California, San Francisco, San Francisco, CA 91343, United States. CA 91343, United States. CA 91343, United States. Electronic address: sanjay.kakar@ucsf.edu.
Journal:Hum Pathol. 2017 Jul;65:187-193. doi: 10.1016/j.humpath.2017.05.012. Epub 2017 May 24.

3:Microcarcinoid arising in patients with long-standing ulcerative colitis: histological analysis.
Authors:Kanada S, Sugita A, Mikami T, Ohashi K, Hayashi H
Institution:Department of Pathology, Yokohama Municipal Citizen's Hospital, Yokohama 240-0062, Japan; Department of Pathology, Toho University School of Medicine, Tokyo 143-8540, Japan; Department of Pathology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan. Electronic address: sachie.kanada@med.toho-u.ac.jp. Yokohama 240-0062, Japan. Japan. Yokohama 236-0004, Japan. 240-0062, Japan.
Journal:Hum Pathol. 2017 Jun;64:28-36. doi: 10.1016/j.humpath.2017.04.001. Epub 2017 Apr 17.

4:Phase III Prospective Randomized Comparison Trial of Depot Octreotide Plus Interferon Alfa-2b Versus Depot Octreotide Plus Bevacizumab in Patients With Advanced Carcinoid Tumors: SWOG S0518.
Authors:Yao JC, Guthrie KA, Moran C, Strosberg JR, Kulke MH, Chan JA, LoConte N, McWilliams RR, Wolin EM, Mattar B, McDonough S, Chen H, Blanke CD, Hochster HS
Institution:James C. Yao and Cesar Moran, MD Anderson Cancer Center, Houston, TX; Katherine A. Guthrie and Shannon McDonough, Fred Hutchinson Cancer Research Center, Seattle, WA; Jonathan R. Strosberg, H. Lee Moffitt Cancer Center, Tampa, FL; Matthew H. Kulke and Jennifer A. Chan, Dana Farber Cancer Institute, Boston, MA; Noelle LoConte, University of Wisconsin, Carbone Cancer Center, Madison, WI; Robert R. McWilliams, Mayo Clinic College of Medicine, Rochester, MN; Edward M. Wolin, University of Kentucky, Lexington, KY; Edward M. Wolin, Montifiore Einstein Cancer Center, New York, NY; Bassam Mattar, Wichita NCORP/Cancer Center of Kansas, Wichita, KS; Helen Chen, NCI Cancer Therapy Evaluation Program, Bethesda, MD; Charles D. Blanke, Oregon Health & Science University, Portland, OR; and Howard S. Hochster, Yale Cancer Center, New Haven, CT.
Journal:J Clin Oncol. 2017 May 20;35(15):1695-1703. doi: 10.1200/JCO.2016.70.4072. Epub 2017 Apr 6.

5:Retrospective review of serotonergic medication tolerability in patients with neuroendocrine tumors with biochemically proven carcinoid syndrome.
Authors:Shi DD, Yuppa DP, Dutton T, Brais LK, Minden SL, Braun IM, Kulke MH, Chan JA, Meyer FL
Institution:Harvard Medical School, Boston, Massachusetts. Institute, Boston, Massachusetts. Massachusetts. Massachusetts. Institute, Boston, Massachusetts. Massachusetts. Massachusetts. Institute, Boston, Massachusetts.
Journal:Cancer. 2017 Jul 15;123(14):2735-2742. doi: 10.1002/cncr.30633. Epub 2017 Mar 7.

6:Pediatric neuroendocrine carcinoid tumors: Management, pathology, and imaging findings in a pediatric referral center.
Authors:Degnan AJ, Tocchio S, Kurtom W, Tadros SS
Institution:Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Pittsburgh, Pennsylvania. Pennsylvania. Virginia. Florida. Pennsylvania. Pittsburgh, Pennsylvania. Pennsylvania.
Journal:Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26477. Epub 2017 Feb 16.

7:Advances in the Diagnosis and Management of Well-Differentiated and Intermediate-Differentiated Neuroendocrine Tumors of the Lung.
Authors:Wolin EM
Institution:Montefiore Einstein Center for Cancer Care, Bronx, NY. Electronic address: ewolin@montefiore.org.
Journal:Chest. 2017 May;151(5):1141-1146. doi: 10.1016/j.chest.2016.06.018. Epub 2016 Jun 29.

8:Deletion of Men1 and somatostatin induces hypergastrinemia and gastric carcinoids.
Authors:Sundaresan S, Kang AJ, Hayes MM, Choi EK, Merchant JL
Institution:Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA. Michigan, Ann Arbor, Michigan, USA. Michigan, Ann Arbor, Michigan, USA. Michigan, Ann Arbor, Michigan, USA. Arbor, Michigan, USA.
Journal:Gut. 2017 Jun;66(6):1012-1021. doi: 10.1136/gutjnl-2015-310928. Epub 2016 Feb 9.

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