Polycystic Ovary Syndrome
June 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Polycystic Ovary Syndrome abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Polycystic Ovary Syndrome. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Polycystic Ovary Syndrome. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Polycystic Ovary Syndrome every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:The Effect of Vitamin D Supplementation on the Androgenic Profile in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Clinical Trials.
Authors:Azadi-Yazdi M, Nadjarzadeh A, Khosravi-Boroujeni H, Salehi-Abargouei A
Institution:Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Medical Sciences, Yazd, Iran. Queensland, Australia. Medical Sciences, Yazd, Iran.
Journal:Horm Metab Res. 2017 Mar;49(3):174-179. doi: 10.1055/s-0043-103573. Epub 2017 Mar 28.

2:The effect of alfacalcidiol and metformin on metabolic disturbances in women with polycystic ovary syndrome.
Authors:Figurova J, Dravecka I, Petrikova J, Javorsky M, Lazurova I
Journal:Horm Mol Biol Clin Investig. 2017 Mar 1;29(3):85-91. doi: 10.1515/hmbci-2016-0039.

3:Short-term effectiveness of low dose liraglutide in combination with metformin versus high dose liraglutide alone in treatment of obese PCOS: randomized trial.
Authors:Jensterle M, Kravos NA, Goricar K, Janez A
Institution:Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Zaloska 7, Ljubljana, SI-1000, Slovenia. Centre Ljubljana, Zaloska 7, Ljubljana, SI-1000, Slovenia. trg 2, Ljubljana, 1000, Slovenia. Centre Ljubljana, Zaloska 7, Ljubljana, SI-1000, Slovenia. andrej.janez@kclj.si.
Journal:BMC Endocr Disord. 2017 Jan 31;17(1):5. doi: 10.1186/s12902-017-0155-9.

4:Metformin during ovulation induction with gonadotrophins followed by timed intercourse or intrauterine insemination for subfertility associated with polycystic ovary syndrome.
Authors:Bordewijk EM, Nahuis M, Costello MF, Van der Veen F, Tso LO, Mol BW, van Wely M
Institution:University of Amsterdam, Amsterdam, Netherlands, 1105 AZ. Royal Hospital for Women and IVF Australia, Barker Street, Randwick, Sydney, Australia, NSW 2031. Amsterdam, Meibergdreef 9, Amsterdam, Netherlands, 1105 AZ. Almeida, 86 - AP. 71, Sao Paulo, Sao Paulo, Brazil, 04042-034. Institute, The University of Adelaide, Level 3, Medical School South Building, Frome Road, Adelaide, South Australia, Australia, SA 5005. Amsterdam, Meibergdreef 9, Amsterdam, Netherlands, 1105 AZ.
Journal:Cochrane Database Syst Rev. 2017 Jan 24;1:CD009090. doi: 10.1002/14651858.CD009090.pub2.

5:Increased risk of disordered eating in polycystic ovary syndrome.
Authors:Lee I, Cooney LG, Saini S, Smith ME, Sammel MD, Allison KC, Dokras A
Institution:Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. of Pennsylvania, Philadelphia, Pennsylvania. of Pennsylvania, Philadelphia, Pennsylvania. Pennsylvania. of Pennsylvania, Philadelphia, Pennsylvania; Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Pennsylvania, Philadelphia, Pennsylvania. of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: adokras@obgyn.upenn.edu.
Journal:Fertil Steril. 2017 Mar;107(3):796-802. doi: 10.1016/j.fertnstert.2016.12.014. Epub 2017 Jan 16.

6:Cardiometabolic Risks in Polycystic Ovary Syndrome: Non-Traditional Risk Factors and the Impact of Obesity.
Authors:Chiu WL, Boyle J, Vincent A, Teede H, Moran LJ
Institution:Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, VIC, Australia.
Journal:Neuroendocrinology. 2017;104(4):412-424. doi: 10.1159/000455233. Epub 2016 Dec 23.

7:Anti-Mullerian hormone and polycystic ovary syndrome.
Authors:Lebkowska A, Kowalska I
Institution:Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Poland. irinak@poczta.onet.pl.
Journal:Endokrynol Pol. 2017;68(1):74-78. doi: 10.5603/EP.a2016.0065. Epub 2016 Dec 5.

8:Combining treatment with myo-inositol and D-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients.
Authors:Monastra G, Unfer V, Harrath AH, Bizzarri M
Institution:a Visiting scientist at the Systems Biology Group, Department of Experimental Medicine, University la Sapienza , Rome , Italy. , Switzerland. Saudi Arabia , and. Sapienza , Rome , Italy.
Journal:Gynecol Endocrinol. 2017 Jan;33(1):1-9. doi: 10.1080/09513590.2016.1247797. Epub 2016 Nov 29.

9:Female infertility, infertility-associated diagnoses, and comorbidities: a review.
Authors:Hanson B, Johnstone E, Dorais J, Silver B, Peterson CM, Hotaling J
Institution:Department of Obstetrics and Gynecology, University of Utah, 50 N Medical Drive, Salt Lake City, UT, 84132, USA. brent.hanson@hsc.utah.edu. Salt Lake City, UT, USA. City, UT, 84108, USA. Salt Lake City, UT, USA. City, UT, 84108, USA. Salt Lake City, UT, 84132, USA. Salt Lake City, UT, USA. City, UT, 84108, USA. Urology and Men's Health, 675 Arapeen Way, Suite 205, Salt Lake City, UT, 84108, USA.
Journal:J Assist Reprod Genet. 2017 Feb;34(2):167-177. doi: 10.1007/s10815-016-0836-8. Epub 2016 Nov 5.

10:Effects of Metformin on Endocrine and Metabolic Parameters in Patients with Polycystic Ovary Syndrome.
Authors:Zahra M, Shah M, Ali A, Rahim R
Institution:Department of Physiology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan. University, Peshawar, Pakistan. University, Peshawar, Pakistan. Hospital, Peshawar, Pakistan.
Journal:Horm Metab Res. 2017 Feb;49(2):103-108. doi: 10.1055/s-0042-119041. Epub 2016 Nov 3.

11:Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS).
Authors:Fruzzetti F, Perini D, Russo M, Bucci F, Gadducci A
Institution:a Department of Obstetrics and Gynecology , University of Pisa , Pisa , Italy.
Journal:Gynecol Endocrinol. 2017 Jan;33(1):39-42. doi: 10.1080/09513590.2016.1236078. Epub 2016 Nov 3.

12:Leptin Levels in Women With Polycystic Ovary Syndrome: A Systematic Review and a Meta-Analysis.
Authors:Zheng SH, Du DF, Li XL
Institution:1 Department of Gynecology, OB/GYN Hospital, Fudan University, Shanghai, China. Shanghai, China.
Journal:Reprod Sci. 2017 May;24(5):656-670. doi: 10.1177/1933719116670265. Epub 2016 Oct 26.

13:Long and irregular menstrual cycles, polycystic ovary syndrome, and ovarian cancer risk in a population-based case-control study.
Authors:Harris HR, Titus LJ, Cramer DW, Terry KL
Institution:Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109. Harvard Medical School, Boston, MA, 02115. Dartmouth, Norris Cotton Cancer Center, NH, 03755, Lebanon. Harvard Medical School, Boston, MA, 02115. MA, 02115. Harvard Medical School, Boston, MA, 02115. MA, 02115.
Journal:Int J Cancer. 2017 Jan 15;140(2):285-291. doi: 10.1002/ijc.30441. Epub 2016 Oct 6.

14:Sexual function and hormonal profiles in women with and without polycystic ovary syndrome: a population-based study.
Authors:Noroozzadeh M, Tehrani FR, Mobarakabadi SS, Farahmand M, Dovom MR
Institution:Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. School, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Journal:Int J Impot Res. 2017 Jan;29(1):1-6. doi: 10.1038/ijir.2016.35. Epub 2016 Sep 22.

15:MANAGEMENT OF ENDOCRINE DISEASE: Morbidity in polycystic ovary syndrome.
Authors:Glintborg D, Andersen M
Institution:Department of EndocrinologyOdense University Hospital, Odense C, Denmark dorte.glintborg@rsyd.dk.
Journal:Eur J Endocrinol. 2017 Feb;176(2):R53-R65. Epub 2016 Sep 6.

16:Evaluation of cardiac risk marker levels in obese and non-obese patients with polycystic ovaries.
Authors:Elci E, Kaya C, Cim N, Yildizhan R, Elci GG
Institution:a Van Ipekyolu Maternity and Children's Disease Hospital, Clinic of Obstetrics and Gynecology , Van , Turkey. and Gynecology , Istanbul , Turkey , and. Gynecology , Van , Turkey. Gynecology , Van , Turkey. Gynecology , Van , Turkey.
Journal:Gynecol Endocrinol. 2017 Jan;33(1):43-47. doi: 10.1080/09513590.2016.1203893. Epub 2016 Jul 16.

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