Polycystic Kidney Disease
June 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Polycystic Kidney Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Polycystic Kidney Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Polycystic Kidney Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Polycystic Kidney Disease every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Urine Osmolality, Response to Tolvaptan, and Outcome in Autosomal Dominant Polycystic Kidney Disease: Results from the TEMPO 3:4 Trial.
Authors:Devuyst O, Chapman AB, Gansevoort RT, Higashihara E, Perrone RD, Torres VE, Blais JD, Zhou W, Ouyang J, Czerwiec FS
Institution:Institute of Physiology, University of Zurich, Zurich, Switzerland; olivier.devuyst@uzh.ch. Center Groningen, University of Groningen, Groningen, The Netherlands. University School of Medicine, Boston, Massachusetts. Clinic, Rochester, Minnesota; and.
Journal:J Am Soc Nephrol. 2017 May;28(5):1592-1602. doi: 10.1681/ASN.2016040448. Epub 2016 Dec 5.

2:Tolvaptan and Kidney Pain in Patients With Autosomal Dominant Polycystic Kidney Disease: Secondary Analysis From a Randomized Controlled Trial.
Authors:Casteleijn NF, Blais JD, Chapman AB, Czerwiec FS, Devuyst O, Higashihara E, Leliveld AM, Ouyang J, Perrone RD, Torres VE, Gansevoort RT
Institution:Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. University of Zurich, Zurich, Switzerland. Groningen, Groningen, the Netherlands. Medicine, Boston, MA. Clinic, Rochester, MN. Groningen, Groningen, the Netherlands. Electronic address: r.t.gansevoort@umcg.nl.
Journal:Am J Kidney Dis. 2017 Feb;69(2):210-219. doi: 10.1053/j.ajkd.2016.08.028. Epub 2016 Nov 14.

3:Predictors of rapid disease progression in autosomal dominant polycystic kidney disease.
Authors:Corradi V, Gastaldon F, Caprara C, Giuliani A, Martino F, Ferrari F, Ronco C
Institution:Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy - valentina.corradi@ulssvicenza.it. Italy - valentina.corradi@ulssvicenza.it. Vicenza, Italy. Italy. Vicenza, Italy. Vicenza, Italy. Italy. Vicenza, Italy. Italy.
Journal:Minerva Med. 2017 Feb;108(1):43-56. doi: 10.23736/S0026-4806.16.04830-8. Epub 2016 Oct 4.

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