| | Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.
Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Parkinson's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Parkinson's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Parkinson's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.
We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Parkinson's Disease every 3 months. Thank you for your ongoing subscription to this publication.
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.
| Authors: | Payne K, Walls B, Wojcieszek J |
| Institution: | Department of Neurology, Indiana University School of Medicine, 355 West 16th Street, Suite 4700, Indianapolis, IN 46202, USA. Electronic address: paynekk@iu.edu. | | Journal: | Med Clin North Am. 2019 Nov;103(6):1055-1075. doi: 10.1016/j.mcna.2019.08.003. Epub 2019 Aug 31. |
| Authors: | Fujioka S, Yoshida R, Nose K, Hayashi Y, Mishima T, Fukae J, Kitano K, Kikuchi H, Tsuboi Y |
| Institution: | Department of Neurology, Murakami Karindoh Hospital, Fukuoka, Japan. tsuboi@cis.fukuoka-u.ac.jp. | | Journal: | Neurol Neurochir Pol. 2019;53(4):291-295. doi: 10.5603/PJNNS.a2019.0036. Epub 2019 Aug 23. |
| Authors: | Siegert C, Hauptmann B, Jochems N, Schrader A, Deck R |
| Institution: | Department Rehabilitation Sciences, Institute for Social Medicine and Epidemiology, University of Lubeck, Ratzeburger Allee 160, 23562, Lubeck, Germany. carolin.siegert@uksh.de. Hamburg, Germany. Germany. Germany. | | Journal: | BMC Neurol. 2019 Jun 25;19(1):143. doi: 10.1186/s12883-019-1355-x. |
| Authors: | Zhong R, Chen Q, Zhang X, Li M, Lin W |
| Institution: | Department of Neurology. Lin Province, China. | | Journal: | Medicine (Baltimore). 2019 Jun;98(24):e16082. doi: 10.1097/MD.0000000000016082. |
| Authors: | Zhao Y, Dzamko N |
| Institution: | Brain and Mind Centre, Central Clinical School, University of Sydney, Camperdown, NSW, 2050, Australia. | | Journal: | Drugs. 2019 Jul;79(10):1037-1051. doi: 10.1007/s40265-019-01139-4. |
| Authors: | Lyons KE, Pahwa R, Hermanowicz N, Davis T, Pagan F, Isaacson S |
| Institution: | a Department of Neurology , University of Kansas Medical Center , Kansas City , KS , USA. KS , USA. , USA. DC , USA. FL , USA. | | Journal: | Expert Rev Clin Pharmacol. 2019 Jul;12(7):681-691. doi: 10.1080/17512433.2019.1623669. Epub 2019 Jun 13. |
| Authors: | Ryan M, Eatmon CV, Slevin JT |
| Institution: | a Department of Pharmacy Practice and Science , University of Kentucky College of Pharmacy , Lexington , KY , USA. Healthcare System , Lexington , KY , USA. of Kentucky College of Medicine , Lexington , KY , USA. | | Journal: | Expert Opin Pharmacother. 2019 Aug;20(11):1351-1363. doi: 10.1080/14656566.2019.1612877. Epub 2019 May 23. |
| Authors: | Li J, Hao J |
| Institution: | * School of Pharmacy, Key laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, Hebei, P. R. China. Pomona, CA 91766, USA. Health Sciences, Pomona, CA 91766, USA. | | Journal: | Am J Chin Med. 2019;47(4):769-785. doi: 10.1142/S0192415X1950040X. Epub 2019 May 15. |
| Authors: | Bernardo WM, Rubira C, Silvinato A |
| Institution: | Brazilian Medical Association, Rua Sao Carlos do Pinhal, 324 - Bela Vista, Sao Paulo - SP, Brasil. Paulo - SP, Brasil. Paulo - SP, Brasil. | | Journal: | Rev Assoc Med Bras (1992). 2019 May 2;65(4):541-546. doi: 10.1590/1806-9282.65.4.541. |
| Authors: | Staff NP, Jones DT, Singer W |
| Institution: | Department of Neurology, Mayo Clinic, Rochester, MN. Electronic address: staff.nathan@mayo.edu. | | Journal: | Mayo Clin Proc. 2019 May;94(5):892-905. doi: 10.1016/j.mayocp.2019.01.001. |
| Authors: | Iijima M, Orimo S, Terashi H, Suzuki M, Hayashi A, Shimura H, Mitoma H, Kitagawa K, Okuma Y |
| Institution: | a Department of Neurology , Tokyo Women's Medical University , Tokyo , Japan. School of Medicine , Tokyo , Japan. Japan. Japan. Japan. | | Journal: | Expert Opin Pharmacother. 2019 Aug;20(11):1405-1411. doi: 10.1080/14656566.2019.1614167. Epub 2019 May 28. |
| Authors: | Fabbri M, Pongmala C, Artusi CA, Romagnolo A, Rizzone MG, Zibetti M, Lopiano L |
| Institution: | Department of Neuroscience "Rita Levi Montalcini", University of Torino, Turin, Italy. Lisbon, Portugal. Italy. | | Journal: | Acta Neurol Scand. 2019 Aug;140(2):157-161. doi: 10.1111/ane.13110. Epub 2019 May 13. |
| Authors: | Raza C, Anjum R, Shakeel NUA |
| Institution: | Department of Zoology, Government College University, Lahore 54000, Pakistan. Electronic address: chandraza@gcu.edu.pk. | | Journal: | Life Sci. 2019 Jun 1;226:77-90. doi: 10.1016/j.lfs.2019.03.057. Epub 2019 Apr 10. |
| Authors: | Fernie BA, Spada MM, Brown RG |
| Institution: | Department of Psychology. | | Journal: | Health Psychol. 2019 Jun;38(6):518-526. doi: 10.1037/hea0000736. Epub 2019 Apr 11. |
| Authors: | Avila A, Caballol N, Martin-Baranera M, Gomez-Ruiz I, Balague-Marmana M, Planas-Ballve A, Cardona X |
| Institution: | Department of Neurology, Hospital Sant Joan Despi Moises Broggi and Hospital General de l'Hospitalet, Consorci Sanitari Integral, Barcelona, Spain.; Department of Clinical Epidemiology, Hospital Sant Joan Despi Moises Broggi and Hospital General de l'Hospitalet, Consorci Sanitari Integral, Barcelona, Spain.; Department of Psychiatry, Hospital Sant Joan Despi Moises Broggi and Hospital General de l'Hospitalet, Consorci Sanitari Integral, Barcelona, Spain. | | Journal: | Acta Neurol Scand. 2019 Jul;140(1):23-31. doi: 10.1111/ane.13096. Epub 2019 Apr 22. |
| Authors: | Balash Y, Korczyn AD, Migirov AA, Gurevich T |
| Institution: | Movement Disorders Unit, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel. | | Journal: | Acta Neurol Scand. 2019 Jul;140(1):17-22. doi: 10.1111/ane.13095. Epub 2019 Apr 23. |
| Authors: | Dinda B, Dinda M, Kulsi G, Chakraborty A, Dinda S |
| Institution: | Department of Chemistry, Tripura University, Suryamaninagar, Agartala, Tripura, 799 022, India. Electronic address: dindabtu@gmail.com. of Medicine, Charlottesvile, 1300 Jefferson Park Ave, VA, 22908, USA. 151742, Republic of Korea. 799 022, India. India. | | Journal: | Eur J Med Chem. 2019 May 1;169:185-199. doi: 10.1016/j.ejmech.2019.03.009. Epub 2019 Mar 8. |
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What Our Customers Are Saying... "I ordered the MediFocus Guidebook on Parkinson's Disease for my father who has had this condition for about 15 years. It was extremely useful to learn about the medications that are used to treat Parkinson's as well as the side-effects. I had read a lot of articles about Parkinson's on the Internet but they were all very general and vague. Your Guidebook provided excellent and comprehensive information from the medical perspective. Thanks for a very useful resource that is much needed today on the Web."
M.L.
Russelsheim, Germany
"I found your Guidebook on Parkinson's to be very informative for me, the patient, and for my husband. I am in the process of changing my medication and the book explained more to me than the doctor attempted to. I am now more aware of what to expect. It also offered valuable advice for the caregiver. Thank you."
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Palm Spring, California
"The Medifocus Guide to Parkinson's Disease was useful, informative, and allowed me to grasp the current fundamentals of treatment. I have recommended it to two of my ex-patients whom I know will find it readable and helpful to their needs."
G.B.
Research Triangle Park, NC
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