Parkinson's Disease
April 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Parkinson's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Parkinson's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Parkinson's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Parkinson's Disease every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Acupuncture as Adjuvant Therapy for Sleep Disorders in Parkinson's Disease.
Authors:Aroxa FH, Gondim IT, Santos EL, Coriolano MD, Asano AG, Asano NM
Institution:Academic of Medicine graduation of Federal University of Pernambuco - Recife, Pernambuco (PE), Brazil. Recife (PE), Brazil. Recife (PE), Brazil. Recife (PE), Brazil. Recife (PE), Brazil. Brazil. Electronic address: nadjaasano@gmail.com.
Journal:J Acupunct Meridian Stud. 2017 Jan;10(1):33-38. doi: 10.1016/j.jams.2016.12.007. Epub 2017 Jan 11.

2:Opicapone for the treatment of Parkinson's disease.
Authors:Rodrigues FB, Ferreira JJ
Institution:a Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine , University of Lisbon , Lisboa , Portugal. Medicine , University of Lisbon , Lisbon , Portugal. , London , UK. University of Lisbon , Lisboa , Portugal. Medicine , University of Lisbon , Lisbon , Portugal.
Journal:Expert Opin Pharmacother. 2017 Mar;18(4):445-453. doi: 10.1080/14656566.2017.1294683. Epub 2017 Feb 22.

3:Key clinical milestones 15 years and onwards after DBS-STN surgery-A retrospective analysis of patients that underwent surgery between 1993 and 2001.
Authors:Constantinescu R, Eriksson B, Jansson Y, Johnels B, Holmberg B, Gudmundsdottir T, Renck A, Berglund P, Bergquist F
Institution:Department of Neurology, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden. Electronic address: Radu.Constantinescu@vgregion.se. Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden. Trollhattan, Sweden. Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden. Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden. Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden. Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden. Molndal, Sweden. Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden.
Journal:Clin Neurol Neurosurg. 2017 Mar;154:43-48. doi: 10.1016/j.clineuro.2017.01.010. Epub 2017 Jan 18.

4:Clinical effectiveness of acupuncture on Parkinson disease: A PRISMA-compliant systematic review and meta-analysis.
Authors:Lee SH, Lim S
Institution:aDepartment of Applied Korean Medicine, College of Korean Medicine, Graduate School, Kyung Hee University bResearch Group of Pain and Neuroscience, WHO Collaborating Center for Traditional Medicine, East-West Medical Research Institute cDepartment of Meridian and Acupoint, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Journal:Medicine (Baltimore). 2017 Jan;96(3):e5836. doi: 10.1097/MD.0000000000005836.

5:Impact of autonomic dysfunctions on the quality of life in Parkinson's disease patients.
Authors:Tomic S, Rajkovaca I, Pekic V, Salha T, Misevic S
Institution:Clinical Department of Neurology, Osijek University Hospital Center, J. Huttlera 4, 31000, Osijek, Croatia. svetlana.tomic@vip.hr. Croatia. svetlana.tomic@vip.hr. Croatia. 4, 31000, Osijek, Croatia. Croatia. Croatia. 4, Osijek, Croatia. 4, 31000, Osijek, Croatia.
Journal:Acta Neurol Belg. 2017 Mar;117(1):207-211. doi: 10.1007/s13760-016-0739-6. Epub 2016 Dec 27.

6:Re-emergent tremor in Parkinson's disease: Clinical and accelerometric properties.
Authors:Ayturk Z, Yilmaz R, Akbostanci MC
Institution:Turgut Ozal University, Faculty of Medicine, Department of Neurology, Ankara, Turkey. Electronic address: zubeydeayturk@yahoo.com. (HIH), University of Tuebingen, Tuebingen, Germany. Electronic address: rezzak.yilmaz@uni-tuebingen.de. Electronic address: Cenk.Akbostanci@medicine.ankara.edu.tr.
Journal:J Clin Neurosci. 2017 Mar;37:31-33. doi: 10.1016/j.jocn.2016.11.007. Epub 2016 Dec 22.

7:Nonmotor symptoms in patients with Parkinson disease: A cross-sectional observational study.
Authors:Zhang TM, Yu SY, Guo P, Du Y, Hu Y, Piao YS, Zuo LJ, Lian TH, Wang RD, Yu QJ, Jin Z, Zhang W
Institution:aDepartment of Geriatrics bDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University cChina National Clinical Research Center for Neurological Diseases; Center of Parkinson's Disease, Beijing Institute for Brain Disorders; Beijing Key Laboratory on Parkinson Disease, Beijing, China.
Journal:Medicine (Baltimore). 2016 Dec;95(50):e5400.

8:Switching L-dopa Therapy from Pulsatile to Pulse Administration Reduces Motor Complications in Parkinson's Disease.
Authors:Mostile G, Nicoletti A, Dibilio V, Luca A, Raciti L, Sciacca G, Cicero CE, Vasta R, Donzuso G, Contrafatto D, Zappia M
Institution:Dipartimento "G.F. Ingrassia", Sezione di Neuroscienze, Universita Degli Studi di Catania, Catania, Italy.
Journal:Clin Neuropharmacol. 2017 Jan/Feb;40(1):6-10. doi: 10.1097/WNF.0000000000000186.

9:The efficacy and safety of coenzyme Q10 in Parkinson's disease: a meta-analysis of randomized controlled trials.
Authors:Zhu ZG, Sun MX, Zhang WL, Wang WW, Jin YM, Xie CL
Institution:Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China. University, Wenzhou, 35000, China. University, Wenzhou, 325000, China. Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China. Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China. 69365560@qq.com. University, Wenzhou, 325000, China. xiechenglong1987@sina.com.
Journal:Neurol Sci. 2017 Feb;38(2):215-224. doi: 10.1007/s10072-016-2757-9. Epub 2016 Nov 9.

10:Cognitive impairment in patients with Parkinson's disease: A 30-month follow-up study.
Authors:Chen L, Yu C, Zhang N, Liu J, Liu W
Institution:Department of Clinical Psychology, Jiangsu Province Geriatric Institute, Nanjing, 210024, China. Electronic address: hubbub_kennel@163.com. University, Nanjing, 210029, China. Electronic address: 363422440@qq.com. Medical University, Nanjing, 210029, China. Electronic address: zn6360@126.com. address: g6115124@163.com. University, Nanjing, 210029, China. Electronic address: liuweiguo1111@sina.com.
Journal:Clin Neurol Neurosurg. 2016 Dec;151:65-69. doi: 10.1016/j.clineuro.2016.09.021. Epub 2016 Oct 4.

11:Chinese medicine for idiopathic Parkinson's disease: A meta analysis of randomized controlled trials.
Authors:Wei W, Chen HY, Fan W, Ye SF, Xu YH, Cai J
Institution:College of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. 441000, China. Province, 364000, China. Fuzhou, 350003, China. Medicine, Fuzhou, 350122, China. caij1@163.com.
Journal:Chin J Integr Med. 2017 Jan;23(1):55-61. doi: 10.1007/s11655-016-2618-7. Epub 2016 Oct 27.

12:Pharmacotherapies for Parkinson's disease symptoms related to cholinergic degeneration.
Authors:Perez-Lloret S, Peralta MC, Barrantes FJ
Institution:a Institute of Cardiology Research , University of Buenos Aires, National Research Council (CONICET-ININCA) , Buenos Aires , Argentina. University Hospital , Buenos Aires , Argentina. UCA-CONICET, Faculty of Medical Sciences , Buenos Aires , Argentina.
Journal:Expert Opin Pharmacother. 2016 Dec;17(18):2405-2415. Epub 2016 Nov 7.

13:Falls, fractures and bone density in Parkinson's disease - a cross-sectional study.
Authors:Tassorelli C, Berlangieri M, Buscone S, Bolla M, De Icco R, Baricich A, Pacchetti C, Cisari C, Sandrini G
Institution:a Neurological Rehabilitation Unit , IRCCS National Neurological Institute "C. Mondino" Foundation , Pavia , Italy. Italy. Mondino" Foundation , Pavia , Italy. Italy. Mondino" Foundation , Pavia , Italy. Mondino" Foundation , Pavia , Italy. Mondino" Foundation , Pavia , Italy. Italy. "Maggiore della Carita" , Novara , Italy. Mondino" Foundation , Pavia , Italy. "Maggiore della Carita" , Novara , Italy. Mondino" Foundation , Pavia , Italy. Italy.
Journal:Int J Neurosci. 2017 Apr;127(4):299-304. doi: 10.1080/00207454.2016.1206897. Epub 2016 Jul 20.

14:Observational study of quality of life of Parkinson's patients and their caregivers.
Authors:Corallo F, De Cola MC, Lo Buono V, Di Lorenzo G, Bramanti P, Marino S
Institution:IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy. University of Messina, Messina, Italy.
Journal:Psychogeriatrics. 2017 Mar;17(2):97-102. doi: 10.1111/psyg.12196. Epub 2016 Jun 24.

15:Deep Brain Stimulation Target Selection for Parkinson's Disease.
Authors:Honey CR, Hamani C, Kalia SK, Sankar T, Picillo M, Munhoz RP, Fasano A, Panisset M
Institution:1Division of Neurosurgery,University of British Columbia,Vancouver,British Columbia. of Alberta,Edmonton,Alberta. Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario. Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario. Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario. Montreal Health Centre,Montreal,Quebec,Canada.
Journal:Can J Neurol Sci. 2017 Jan;44(1):3-8. doi: 10.1017/cjn.2016.22. Epub 2016 Mar 15.

16:Technology-aided leisure and communication: Opportunities for persons with advanced Parkinson's disease.
Authors:Lancioni G, Singh N, O'Reilly M, Sigafoos J, D'Amico F, Sasanelli G, Denitto F, Lang R
Institution:a Department of Neuroscience and Sense Organs , University of Bari , Bari , Italy. USA. Wellington , New Zealand. , USA.
Journal:Dev Neurorehabil. 2016 Dec;19(6):398-404. Epub 2015 Mar 31.

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