| | Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.
Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Parkinson's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Parkinson's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Parkinson's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.
We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Parkinson's Disease every 3 months. Thank you for your ongoing subscription to this publication.
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.
| Authors: | Patel N, LeWitt P, Neikrug AB, Kesslak P, Coate B, Ancoli-Israel S |
| Institution: | Parkinson's Disease and Movement Disorders Program, Henry Ford Hospital, West Bloomfield, MI. Bloomfield, MI. Irvine. Jolla, CA. | | Journal: | Clin Neuropharmacol. 2018 Nov/Dec;41(6):210-215. doi: 10.1097/WNF.0000000000000307. |
| Authors: | Torti M, Vacca L, Stocchi F |
| Institution: | a Center for Parkinson's Disease , IRCCS San Raffaele Pisana , Rome , Italy. | | Journal: | Expert Opin Pharmacother. 2018 Nov;19(16):1821-1828. doi: 10.1080/14656566.2018.1524876. Epub 2018 Oct 11. |
| Authors: | Dashtipour K, Tafreshi A, Lee J, Crawley B |
| Institution: | Department of Neurology, Loma Linda University School of Medicine, Loma Linda, CA, USA. CA, USA. CA, USA. Linda, CA, USA. | | Journal: | Neurodegener Dis Manag. 2018 Oct;8(5):337-348. doi: 10.2217/nmt-2018-0021. Epub 2018 Sep 18. |
| Authors: | Peng L, Fu J, Ming Y, Zeng S, He H, Chen L |
| Institution: | Department of Neurosurgery. Luzhou, China. | | Journal: | Medicine (Baltimore). 2018 Aug;97(35):e12153. doi: 10.1097/MD.0000000000012153. |
| Authors: | Stoker TB, Barker RA |
| Institution: | John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, E.D. Adrian Building, Forvie Site, Robinson Way, Cambridge, CB2 0PY, UK. tbs26@cam.ac.uk.; Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK. tbs26@cam.ac.uk. | | Journal: | BioDrugs. 2018 Aug;32(4):357-366. doi: 10.1007/s40259-018-0294-1. |
| Authors: | Brandao P, Grippe TC, Modesto LC, Ferreira AGF, Silva FMD, Pereira FF, Lobo ME, Allam N, Freitas TDS, Munhoz RP |
| Institution: | Universidade de Brasilia, Laboratorio de Neurociencia e Comportamento, Brasilia DF, Brasil. Brasil. Brasil. DF, Brasil. Brasil. University Health Network, Toronto, Canada. | | Journal: | Arq Neuropsiquiatr. 2018 Jun;76(6):411-420. doi: 10.1590/0004-282X20180048. |
| Authors: | Vargas AP, Cardoso FEC |
| Institution: | Rede SARAH de Hospitais de Reabilitacao, Departamento de Neurologia, Belo Horizonte MG, Brasil. Departamento de Clinica Medica, Servico de Neurologia, Belo Horizonte MG, Brasil. | | Journal: | Arq Neuropsiquiatr. 2018 Jun;76(6):399-410. doi: 10.1590/0004-282X20180052. |
| Authors: | Mendes Filho D, Ribeiro PDC, Oliveira LF, de Paula DRM, Capuano V, de Assuncao TSF, da Silva VJD |
| Institution: | Departments of Physiology, Biological and Natural Sciences Institute. Medical School, Sao Jose do Rio Preto, SP. (INCT-REGENERA-CNPq), Rio de Janeiro, RJ. Federal University, Uberaba. Belo Horizonte, MG, Brazil. Federal University, Uberaba. | | Journal: | Neurologist. 2018 Jul;23(4):141-147. doi: 10.1097/NRL.0000000000000188. |
| Authors: | Sawada H, Umemura A, Kohsaka M, Tomita S, Park K, Oeda T, Yamamoto K |
| Institution: | a Department of Neurology & Clinical Research Center , Utano National Hospital , Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. Kyoto , Japan. | | Journal: | Expert Opin Pharmacother. 2018 Jul;19(10):1071-1076. doi: 10.1080/14656566.2018.1485650. Epub 2018 Jun 25. |
| Authors: | Muller T, Mohr JD |
| Institution: | a Department of Neurology , St. Joseph Hospital Berlin-Weissensee , Berlin , Germany. Germany. | | Journal: | Expert Opin Pharmacother. 2018 Jun;19(9):1003-1011. doi: 10.1080/14656566.2018.1484108. Epub 2018 Jun 18. |
| Authors: | de Andrade Teles RB, Diniz TC, Costa Pinto TC, de Oliveira Junior RG, Gama E Silva M, de Lavor EM, Fernandes AWC, de Oliveira AP, de Almeida Ribeiro FPR, da Silva AAM, Cavalcante TCF, Quintans Junior LJ, da Silva Almeida JRG |
| Institution: | Postgraduate Program in Biotechnology, State University of Feira de Santana, 44036-900 Feira de Santana, BA, Brazil. 44036-900 Feira de Santana, BA, Brazil. University of Pernambuco, 50740-521 Recife, PE, Brazil. | | Journal: | Oxid Med Cell Longev. 2018 May 10;2018:7043213. doi: 10.1155/2018/7043213. eCollection 2018. |
| Authors: | Diez-Cirarda M, Ibarretxe-Bilbao N, Pena J, Ojeda N |
| Institution: | Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Bilbao, Spain. | | Journal: | Neural Plast. 2018 May 6;2018:2651918. doi: 10.1155/2018/2651918. eCollection 2018. |
| Authors: | |
| Journal: | Drug Ther Bull. 2018 May;56(5):54-57. doi: 10.1136/dtb.2018.5.0623. |
| Authors: | Scorza FA, Fiorini AC, Scorza CA, Finsterer J |
| Institution: | Disciplina de Neurociencia, Escola Paulista de Medicina/Universidade Federal de Sao Paulo (EPM/UNIFESP), Sao Paulo, Brazil. Electronic address: scorza@unifesp.br. Catolica de Sao Paulo (PUC-SP), Brazil; Departamento de Fonoaudiologia, Escola Paulista de Medicina/Universidade Federal de Sao Paulo (EPM/UNIFESP), Sao Paulo, Brazil. Electronic address: acfiorini@pucsp.br. Sao Paulo (EPM/UNIFESP), Sao Paulo, Brazil. fifigs1@yahoo.de. | | Journal: | J Clin Neurosci. 2018 Jul;53:1-5. doi: 10.1016/j.jocn.2018.04.031. Epub 2018 Apr 26. |
| Authors: | Vescovelli F, Sarti D, Ruini C |
| Institution: | Department of Psychology, University of Bologna, Bologna, Italy. | | Journal: | Acta Neurol Scand. 2018 Jul;138(1):12-23. doi: 10.1111/ane.12946. Epub 2018 Apr 25. |
| Authors: | Park SH, Hwang MS, Park HJ, Shin HK, Baek JU, Choi BT |
| Institution: | 1 Division of Humanities and Social Medicine, School of Korean Medicine, Pusan National University , Yangsan, Republic of Korea.; 2 Division of Meridian and Structural Medicine, School of Korean Medicine, Pusan National University , Yangsan, Republic of Korea. | | Journal: | J Altern Complement Med. 2018 Jul;24(7):733-740. doi: 10.1089/acm.2017.0387. Epub 2018 Mar 27. |
| Authors: | Elkurd MT, Bahroo LB, Pahwa R |
| Institution: | Department of Neurology, Medstar Georgetown University Hospital, Georgetown, Washington DC, USA. Washington DC, USA. | | Journal: | Neurodegener Dis Manag. 2018 Apr;8(2):73-80. doi: 10.2217/nmt-2018-0001. Epub 2018 Mar 22. |
| Authors: | Dalle E, Mabandla MV |
| Institution: | School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, 4000, South Africa. dumessherve@yahoo.fr. | | Journal: | Mol Brain. 2018 Mar 19;11(1):18. doi: 10.1186/s13041-018-0356-9. |
| Authors: | Billingsley KJ, Bandres-Ciga S, Saez-Atienzar S, Singleton AB |
| Institution: | Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, 35 Convent Drive, Bethesda, MD, 20892, USA. singleta@mail.nih.gov.; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, L69 3BX, Liverpool, UK. | | Journal: | Cell Tissue Res. 2018 Jul;373(1):9-20. doi: 10.1007/s00441-018-2817-y. Epub 2018 Mar 13. |
| Authors: | Friedman JH |
| Institution: | a Movement Disorders Program , Butler Hospital , Providence , RI , USA. Providence , RI , USA. | | Journal: | Expert Opin Pharmacother. 2018 Apr;19(5):499-505. doi: 10.1080/14656566.2018.1445721. Epub 2018 Mar 1. |
| Authors: | da Silva FC, Iop RDR, de Oliveira LC, Boll AM, de Alvarenga JGS, Gutierres Filho PJB, de Melo LMAB, Xavier AJ, da Silva R |
| Institution: | University of State of Santa Catarina, Center for Health Sciences and Sports, Adapted Physical Activity Laboratory, Florianopolis, Santa Catarina, Brazil.; University of Brasilia, Faculty of Physical Education, Brasilia, Brazil.; University of Southern Santa Catarina, Medicine Course, Florianopolis, Santa Catarina, Brazil. | | Journal: | PLoS One. 2018 Feb 27;13(2):e0193113. doi: 10.1371/journal.pone.0193113. eCollection 2018. |
| Authors: | Amro MS, Teoh SL, Norzana AG, Srijit D |
| Institution: | Department of Anatomy, Universiti Kebangsaan Malaysia Medical Centre, 56000 Kuala Lumpur, Malaysia. Lumpur, Malaysia. Lumpur, Malaysia. Lumpur, Malaysia. | | Journal: | Clin Ter. 2018 Jan-Feb;169(1):e23-e33. doi: 10.7417/T.2018.2050. |
| Authors: | Castro Caldas A, Teodoro T, Ferreira JJ |
| Institution: | a Neurology Service, Department of Neurosciences , Hospital de Santa Maria , Lisbon , Portugal. Portugal. University Hospitals NHS Foundation Trust , London , United Kingdom. | | Journal: | Expert Opin Drug Saf. 2018 Mar;17(3):331-337. doi: 10.1080/14740338.2018.1433659. |
| Authors: | Jung UJ, Kim SR |
| Institution: | 1 Department of Food Science and Nutrition, Pukyong National University , Busan, Korea. Life Science and Biotechnology, Kyungpook National University , Daegu, Korea. Korea. | | Journal: | J Med Food. 2018 May;21(5):421-432. doi: 10.1089/jmf.2017.4078. Epub 2018 Feb 7. |
| Authors: | Nassif DV, Pereira JS |
| Institution: | Department of Neurology, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, Brazil. Rio de Janeiro, Rio de Janeiro, Brazil. | | Journal: | Psychogeriatrics. 2018 Mar;18(2):143-150. doi: 10.1111/psyg.12302. Epub 2018 Feb 6. |
| Authors: | Sharma A, Kurek J, Morgan JC, Wakade C, Rao SSC |
| Institution: | Division of Gastroenterology/Hepatology, Medical College of Georgia, Augusta University Medical Center, 1120 15th Street, AD-2226, Augusta, GA, 30912, USA. amosharma@augusta.edu.; Parkinson's Foundation Center of Excellence, Movement Disorders Program, Department of Neurology, Medical College of Georgia, Augusta University, Augusta, GA, USA.; Department of Physical Therapy, College of Allied Health Sciences, Augusta University & Charlie Norwood VAMC, Augusta, GA, USA. | | Journal: | Curr Gastroenterol Rep. 2018 Jan 19;20(1):1. doi: 10.1007/s11894-018-0609-x. |
| Authors: | Teixeira FG, Gago MF, Marques P, Moreira PS, Magalhaes R, Sousa N, Salgado AJ |
| Institution: | Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3Bs - PT Government Associate Laboratory, Braga/Guimaraes, Portugal. Electronic address: fabioteixeira@med.uminho.pt.; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3Bs - PT Government Associate Laboratory, Braga/Guimaraes, Portugal; Neurology Department, Hospital da Senhora da Oliveira, EPE, Guimaraes, Portugal. | | Journal: | Drug Discov Today. 2018 Mar;23(3):736-744. doi: 10.1016/j.drudis.2018.01.033. Epub 2018 Jan 12. |
| Authors: | Sudhakar V, Richardson RM |
| Journal: | Prog Neurol Surg. 2018;33:253-264. doi: 10.1159/000481109. Epub 2018 Jan 12. |
| Authors: | Lee PS, Crammond DJ, Richardson RM |
| Journal: | Prog Neurol Surg. 2018;33:207-221. doi: 10.1159/000481105. Epub 2018 Jan 12. |
| Authors: | Cahan LD, Young RF, Li F |
| Journal: | Prog Neurol Surg. 2018;33:149-157. doi: 10.1159/000481083. Epub 2018 Jan 12. |
| Authors: | Parmar M |
| Institution: | Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund University, BMC A11, S-221 84 Lund, Sweden malin.parmar@med.lu.se. | | Journal: | Development. 2018 Jan 8;145(1). pii: 145/1/dev156117. doi: 10.1242/dev.156117. |
| Authors: | Ng JSC |
| Institution: | Palliative medicine physician, Haven of Hope Hospital, Hong Kong, China. ngscj@ha.org.hk. | | Journal: | Ann Palliat Med. 2018 Jul;7(3):296-303. doi: 10.21037/apm.2017.12.02. Epub 2018 Jan 4. |
| Authors: | Nasrolahi A, Mahmoudi J, Akbarzadeh A, Karimipour M, Sadigh-Eteghad S, Salehi R, Farhoudi M |
| Institution: | Molecular Medicine Department, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 51656-87386, Iran. 51666-14756, Iran. 51666-14756, Iran. Tabriz University of Medical Sciences, Tabriz 51656-87386, Iran. of Medical Sciences, Tabriz 51656-87386, Iran. Sciences, Tabriz 51656-87386, Iran. 51666-14756, Iran. Tabriz University of Medical Sciences, Tabriz 51656-87386, Iran. 51666-14756, Iran. of Medical Sciences, Tabriz 51656-87386, Iran. | | Journal: | Rev Neurosci. 2018 Jul 26;29(5):475-489. doi: 10.1515/revneuro-2017-0040. |
| Authors: | Hurtado JDC, Sanchez JPB, Nunes RB, de Oliveira AA |
| Institution: | Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil. ft.jaisonhurtado@gmail.com. Porto Alegre, Rio Grande Do Sul, CEP 90.050-170, Brazil. ft.jaisonhurtado@gmail.com. | | Journal: | Stem Cell Rev. 2018 Apr;14(2):166-176. doi: 10.1007/s12015-017-9798-1. |
| Authors: | Lattanzi S, Grillo E, Brigo F, Silvestrini M |
| Institution: | Neurological Clinic, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Via Conca 71, 60020, Ancona, Italy. alfierelattanzisimona@gmail.com. Verona, Verona, Italy. Polytechnic University, Via Conca 71, 60020, Ancona, Italy. | | Journal: | J Neurol. 2018 Apr;265(4):733-740. doi: 10.1007/s00415-017-8681-y. Epub 2017 Nov 20. |
| Authors: | Sahli ZT, Tarazi FI |
| Institution: | a Department of Psychiatry and Neuroscience Program , Harvard Medical School, McLean Hospital , Belmont , MA , USA. McLean Hospital , Belmont , MA , USA. | | Journal: | Expert Opin Drug Discov. 2018 Jan;13(1):103-110. doi: 10.1080/17460441.2018.1394838. Epub 2017 Oct 31. |
| Authors: | Papagno C, Trojano L |
| Institution: | CIMeC, University of Trento, Trento, Italy. costanza.papagno@unimib.it. 02100, Milan, Italy. costanza.papagno@unimib.it. Ellittico 31, 81100, Caserta, Italy. luigi.trojano@unicampania.it. | | Journal: | Neurol Sci. 2018 Feb;39(2):215-223. doi: 10.1007/s10072-017-3154-8. Epub 2017 Oct 17. |
| Authors: | Erro R, Brigo F, Tamburin S, Zamboni M, Antonini A, Tinazzi M |
| Institution: | Department of Neuroscience, Biomedicine and Movement Science, University of Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy. erro.roberto@gmail.com. University of Salerno, Salerno, Italy. erro.roberto@gmail.com. Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy. Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy. of Verona, Verona, Italy. Universitaria Padua, Padua, Italy. Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy. | | Journal: | J Neurol. 2018 Jan;265(1):12-23. doi: 10.1007/s00415-017-8639-0. Epub 2017 Oct 10. |
| Authors: | Dos Santos Delabary M, Komeroski IG, Monteiro EP, Costa RR, Haas AN |
| Institution: | Physical Education School, Federal University of Rio Grande do Sul, Street Felizardo, 750-Jardim Botanico, Porto Alegre, Rio Grande Do Sul, CEP 90690-200, Brazil. marcela_delabary@yahoo.com.br.; Federal Foundation School of Medical Sciences of Porto Alegre, Street Sarmento Leite, 245 Centro Historico, Porto Alegre, Rio Grande Do Sul, CEP 90050-170, Brazil. | | Journal: | Aging Clin Exp Res. 2018 Jul;30(7):727-735. doi: 10.1007/s40520-017-0836-2. Epub 2017 Oct 4. |
| Authors: | Cardoso F |
| Institution: | Movement Disorders Unit, Neurology Service, Internal Medicine Department, The Federal University of Minas Gerais, Brazil. Electronic address: cardosofe@terra.com.br. | | Journal: | Toxicon. 2018 Jun 1;147:107-110. doi: 10.1016/j.toxicon.2017.08.018. Epub 2017 Aug 23. |
| Authors: | Tambasco N, Romoli M, Calabresi P |
| Institution: | Clinica Neurologica, Azienda Ospedaliera-Universita di Perugia, Perugia, Italy. | | Journal: | Curr Neuropharmacol. 2018;16(8):1239-1252. doi: 10.2174/1570159X15666170510143821. |
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What Our Customers Are Saying... "I ordered the MediFocus Guidebook on Parkinson's Disease for my father who has had this condition for about 15 years. It was extremely useful to learn about the medications that are used to treat Parkinson's as well as the side-effects. I had read a lot of articles about Parkinson's on the Internet but they were all very general and vague. Your Guidebook provided excellent and comprehensive information from the medical perspective. Thanks for a very useful resource that is much needed today on the Web."
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