Reflex Sympathetic Dystrophy
January 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Reflex Sympathetic Dystrophy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Reflex Sympathetic Dystrophy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Reflex Sympathetic Dystrophy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Reflex Sympathetic Dystrophy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Psychiatric Disorders in Complex Regional Pain Syndrome (CRPS): The Role of the Consultation-Liaison Psychiatrist.
Authors:Brinkers M, Rumpelt P, Lux A, Kretzschmar M, Pfau G
Institution:Department of Anaesthesiology and Intensive Care Medicine, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany. Bautzen, Germany. Magdeburg, Magdeburg, Germany.
Journal:Pain Res Manag. 2018 Oct 17;2018:2894360. doi: 10.1155/2018/2894360. eCollection 2018.

2:Successful treatment of complex regional pain syndrome with topical ambroxol: a case series.
Authors:Maihofner C, Schneider S, Bialas P, Gockel H, Beer KG, Bartels M, Kern KU
Institution:Department of Neurology, General Hospital Furth, Jakob-Henle-Strasse 1, 90766 Furth, Germany. Homburg (Saar), Germany. Furth, Germany.
Journal:Pain Manag. 2018 Nov 1;8(6):427-436. doi: 10.2217/pmt-2018-0048. Epub 2018 Nov 5.

3:A new hypothesis for the pathophysiology of complex regional pain syndrome.
Authors:Russo M, Georgius P, Santarelli DM
Institution:Hunter Pain Clinic, 91 Chatham Street, Broadmeadow, NSW 2292, Australia. Electronic address: Australia.
Journal:Med Hypotheses. 2018 Oct;119:41-53. doi: 10.1016/j.mehy.2018.07.026. Epub 2018 Jul 29.

4:Complex regional pain syndrome.
Authors:Thurlow G, Gray B
Institution:Consultant Nurse - Rehabilitation and Pain Management Programmes, RNOH, Brockley Hill, Stanmore, HA7 4LP, UK. Electronic address: Guernsey. Electronic address:
Journal:Int J Orthop Trauma Nurs. 2018 Aug;30:44-47. doi: 10.1016/j.ijotn.2018.03.002. Epub 2018 Mar 19.

5:Complex Regional Pain Syndrome: What the Dermatologist Should Know.
Authors:Qureshi AA, Friedman AJ
Journal:J Drugs Dermatol. 2018 May 1;17(5):532-536.

6:Complex Regional Pain Syndrome Type 1: Diagnosis and Management.
Authors:Lee JW, Lee SK, Choy WS
Institution:* Department of Orthopedic Surgery, Eulji University College of Medicine, Daejeon, Korea. Daejeon, Korea. Daejeon, Korea.
Journal:J Hand Surg Asian Pac Vol. 2018 Mar;23(1):1-10. doi: 10.1142/S2424835518300013.

7:Complex Regional Pain Syndrome, Current Concepts and Treatment Options.
Authors:Urits I, Shen AH, Jones MR, Viswanath O, Kaye AD
Institution:Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Anesthesiology, Lousiana State University Health Science Center, 1542 Tulane Avenue Suite 659, New Orleans, LA, 70112, USA.
Journal:Curr Pain Headache Rep. 2018 Feb 5;22(2):10. doi: 10.1007/s11916-018-0667-7.

8:The Effect of Ketamine Infusion in the Treatment of Complex Regional Pain Syndrome: a Systemic Review and Meta-analysis.
Authors:Zhao J, Wang Y, Wang D
Institution:Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, USA. Philadelphia, USA.
Journal:Curr Pain Headache Rep. 2018 Feb 5;22(2):12. doi: 10.1007/s11916-018-0664-x.

9:Utility of Radionuclide Bone Scintigraphy in Complex Regional Pain Syndrome.
Authors:Howard BA, Roy L, Kaye AD, Pyati S
Institution:Division of Nuclear Medicine, Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. USA. USA. USA. 27710, USA.
Journal:Curr Pain Headache Rep. 2018 Feb 1;22(1):7. doi: 10.1007/s11916-018-0659-7.

10:Spinal Cord Stimulation in Patients With Complex Regional Pain Syndrome: A Possible Target for Immunomodulation?
Authors:Kriek N, Schreurs MWJ, Groeneweg JG, Dik WA, Tjiang GCH, Gultuna I, Stronks DL, Huygen FJPM
Institution:Center for Pain Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands. Netherlands. Netherlands. Netherlands. Hospital, Oosterhout, The Netherlands. Netherlands. Netherlands.
Journal:Neuromodulation. 2018 Jan;21(1):77-86. doi: 10.1111/ner.12704. Epub 2017 Oct 24.

11:Transcranial magnetic stimulation studies in complex regional pain syndrome type I: A review.
Authors:Nardone R, Brigo F, Holler Y, Sebastianelli L, Versace V, Saltuari L, Lochner P, Trinka E
Institution:Department of Neurology, Franz Tappeiner Hospital, Merano, Italy. Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria. Verona, Verona, Italy. Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria. for Neurorehabilitation South Tyrol, Bolzano, Italy. for Neurorehabilitation South Tyrol, Bolzano, Italy. for Neurorehabilitation South Tyrol, Bolzano, Italy. Cognitive Neuroscience, Paracelsus Medical University, Salzburg, Austria. Austria.
Journal:Acta Neurol Scand. 2018 Feb;137(2):158-164. doi: 10.1111/ane.12852. Epub 2017 Oct 3.

12:Prevalence and Cost Analysis of Complex Regional Pain Syndrome (CRPS): A Role for Neuromodulation.
Authors:Elsamadicy AA, Yang S, Sergesketter AR, Ashraf B, Charalambous L, Kemeny H, Ejikeme T, Ren X, Pagadala P, Parente B, Xie J, Lad SP
Institution:Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Journal:Neuromodulation. 2018 Jul;21(5):423-430. doi: 10.1111/ner.12691. Epub 2017 Sep 29.

13:Hand lesion after arthroscopic rotator cuff repair: Association with complex regional pain syndrome.
Authors:Tanesue R, Gotoh M, Mitsui Y, Nakamura H, Honda H, Ohzono H, Shimokobe H, Tokunaga T, Imai T, Okawa T, Shiba N
Institution:Department of Orthopedic Surgery, Kurume University, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan.; Department of Orthopedic Surgery, Kurume University Medical Center, 155-1 Kokubu-machi, Kurume, Fukuoka, 839-0863, Japan. Electronic address:; Division of Rehabilitation Medicine, Keishinkai Hospital, 670-1 Hara-machi, Tosu, Saga, 841-0024, Japan.
Journal:J Orthop Sci. 2018 Jan;23(1):70-74. doi: 10.1016/j.jos.2017.09.007. Epub 2017 Sep 23.

14:Traditional manual acupuncture combined with rehabilitation therapy for shoulder hand syndrome after stroke within the Chinese healthcare system: a systematic review and meta-analysis.
Authors:Peng L, Zhang C, Zhou L, Zuo HX, He XK, Niu YM
Institution:1 Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, China.; 2 Department of Neurology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, China.; 3 Department of Rehabilitation Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, China.
Journal:Clin Rehabil. 2018 Apr;32(4):429-439. doi: 10.1177/0269215517729528. Epub 2017 Sep 13.

15:Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome (CRPS) Recurrence after Amputation for CRPS, and Failure of Conventional Spinal Cord Stimulation.
Authors:Goebel A, Lewis S, Phillip R, Sharma M
Institution:Walton Centre NHS Foundation Trust, Liverpool, U.K.
Journal:Pain Pract. 2018 Jan;18(1):104-108. doi: 10.1111/papr.12582. Epub 2017 May 28.

16:Dorsal Column Stimulation vs. Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome Confined to the Knee: Patients' Preference Following the Trial Period.
Authors:van Bussel CM, Stronks DL, Huygen FJPM
Institution:Center for Pain Medicine, Erasmus MC-University Medical Center, Rotterdam, the Netherlands. Netherlands. Netherlands.
Journal:Pain Pract. 2018 Jan;18(1):87-93. doi: 10.1111/papr.12573. Epub 2017 May 4.

For a FREE PREVIEW of the Medifocus Guidebook on Reflex Sympathetic Dystrophy click here

To purchase a copy of the COMPLETE Medifocus Guidebook on Reflex Sympathetic Dystrophy click here

To subscribe to additional FREE Medifocus Digest Alert on other disease/condition areas click here

Get the Medifocus Guidebook on Reflex Sympathetic Dystrophy...
at a Special 20% Discount

Medifocus Guidebook on Reflex Sympathetic Dystrophy

Updated: January 5, 2019
178 Pages

This one of a kind Guidebook offers:

  • Answers to your critical health questions including the latest treatments, clinical trials, and expert research.
  • High Quality, Professional level information you can trust and understand culled from the latest peer-reviewed journals.
  • Timely, up to date content with free guidebook updates for 1 year.
  • A unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks.
  • Over 130,000 Guidebooks Sold
  • 100% Risk Free Money Back Guarantee


The Medifocus Guidebook on Reflex Sympathetic Dystrophy is available in the following two convenient formats:


Soft-cover book that is available for immediate shipping via either U.S. Priority Mail or International AirMail (outside the U.S.).

  • Regular List Price = $36.95
  • Less 20% Discount = - $7.40
  • Discounted Price = $29.55(excluding shipping & handling)

Order the Printed Guidebook


Available for immediate download as a PDF document.

  • Regular List Price = $27.95
  • Less 20% Discount = - $5.60
  • Discounted Price = $22.35

Order the Digital Guidebook

Order by Phone

Call Toll Free in the U.S.

From Outside the U.S.

You can also receive a 20% discount when you order your Guidebook by phone.

To receive your 20% discount, simply mention the Discount Coupon Code below to the customer service representative taking your order.

Discount Coupon Code for
Phone Orders


Coupon Expires: March 21, 2019

What Our Customers Are Saying...

"Your MediFocus Guidebook on Reflex Sympathetic Dystrophy helped me understand my diagnosis. It gave me a clear insight into what the disorder is about and a way to find out about the treatments for RSD. It also gave me a way to inform those around me. Anyone who has RSD or knows someone who is diagnosed with RSD needs this easy to read and understand Guidebook."
Casper, Wyoming

"I was recently diagnosed with RSD and I purchased the MediFocus Guidebook on this condition. The book was very well written and I immediately gave it to one of my doctors. With the help of the Guidebook, we were able to come up with a better treatment plan to help alleviate my pain. Sincere thanks."
Pennsauken, New Jersey

"I have been seen by some of the best RSD specialists in my area. Each of them told me there was nothing more that could be done for me. I became extremely frustrated and lost all hope of ever getting better. Many times I have searched the Internet for information about RSD and always came up with info I already had. I accidentally came across your website, ordered a book and was absolutely amazed at the amount of information now available to me. Although I have had you book only a short time, I have already discovered some new information. And with so many recent reports from doctors all over the world, perhaps I will come across some sort of treatment I haven't tried yet. The main thing is, I now have hope again thanks to your book. Thank you."
Fonthill, Ontario

Medifocus Digest Alert is published by Medifocus, Inc.
6810 Park Heights Avenue, Suite C5, Baltimore, MD 21215 USA
Copyright © 2019 Medifocus, Inc. All rights reserved.