Trigeminal Neuralgia
December 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Trigeminal Neuralgia abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Trigeminal Neuralgia. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Trigeminal Neuralgia. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Trigeminal Neuralgia every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:The long-term clinical outcomes of microvascular decompression for treatment of trigeminal neuralgia compressed by the vertebra-basilar artery: a case series review.
Authors:Wang X, Wang H, Chen S, Liang H, Wang H, Xu M, Xu L
Institution:Department of Neurosurgery, Daping Hospital, Army Medical University, No. 10 Daping Changjiang Street, Yuzhong District, Chongqing, 400042, China.; Department of Clinical Biochemistry, Southwestern Hospital, Army Medical University, Chongqing, 400038, China.; Department of Neurosurgery, Daping Hospital, Army Medical University, No. 10 Daping Changjiang Street, Yuzhong District, Chongqing, 400042, China.
Journal:BMC Neurol. 2019 Sep 3;19(1):217. doi: 10.1186/s12883-019-1450-z.

2:Efficacy of gabapentin in the treatment of trigeminal neuralgia: A systematic review of randomized controlled trials.
Authors:Ta PCP, Dinh HQ, Nguyen K, Lin S, Ong YL, Ariyawardana A
Institution:College of Medicine and Dentistry, James Cook University, Cairns, QLD, Australia.
Journal:J Investig Clin Dent. 2019 Nov;10(4):e12448. doi: 10.1111/jicd.12448. Epub 2019 Aug 11.

3:Botulinum toxin type A as an alternative way to treat trigeminal neuralgia: a systematic review.
Authors:Ostrowski H, Roszak J, Komisarek O
Institution:Studenckie Kolo Naukowe Chirurgii Szczekowo-Twarzowej oraz Ortognatycznej Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu. Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu. Poznaniu.
Journal:Neurol Neurochir Pol. 2019;53(5):327-334. doi: 10.5603/PJNNS.a2019.0030. Epub 2019 Aug 9.

4:Image Fusion: A Novel Approach in Gamma Knife Surgery Treating Trigeminal Neuralgia.
Authors:Tang K, Zhao Y, Yu J, Gao H, Gao D, Di C, Wang Y
Institution:Department of Neurosurgery, the 309th Hospital of Chinese People's Liberation Army, Beijing, China.
Journal:J Craniofac Surg. 2019 Jul;30(5):e392-e395. doi: 10.1097/SCS.0000000000005307.

5:A systematic review of rescue analgesic strategies in acute exacerbations of primary trigeminal neuralgia.
Authors:Moore D, Chong MS, Shetty A, Zakrzewska JM
Institution:Department of Anaesthesia, Beaumont Hospital, Dublin, Ireland.
Journal:Br J Anaesth. 2019 Aug;123(2):e385-e396. doi: 10.1016/j.bja.2019.05.026. Epub 2019 Jun 15.

6:Trigeminal Neuralgia and Other Facial Neuralgias.
Authors:Wolf A, Kondziolka D
Institution:Center for Advanced Radiosurgery, NYU Langone Medical Center, New York, New York, USA. USA,
Journal:Prog Neurol Surg. 2019;34:273-278. doi: 10.1159/000493074. Epub 2019 May 16.

7:Radiosurgery for trigeminal neuralgia: the state of art.
Authors:Marchetti M, Pinzi V, De Martin E, Ghielmetti F, Fariselli L
Institution:Radiotherapy Unit, Department of Radiosurgery, Fondazione IRCCS Istituto Neurologico C. Besta, Via Giovanni Celoria, 11, 20133, Milano, Italy.
Journal:Neurol Sci. 2019 May;40(Suppl 1):153-157. doi: 10.1007/s10072-019-03814-6.

8:Factors Predicting Successful Outcomes for Percutaneous Radiofrequency Thermocoagulation in Patients With Idiopathic Trigeminal Neuralgia: Implications for Surgical Decision Making.
Authors:Li X, Zheng S, Yang L, Cao Z, Ni J, Zhang Y
Institution:School of Medicine, Tsinghua University, Beijing, China. Corporation (Aerospace Clinical Medical School of Peking University), Beijing, China. University, Beijing, China.
Journal:Pain Pract. 2019 Jun;19(5):491-499. doi: 10.1111/papr.12769. Epub 2019 May 28.

9:Comparing Microvascular Decompression with Gamma Knife Radiosurgery for Trigeminal Neuralgia. A Cost-Effectiveness Analysis.
Authors:Gandhoke GS, Smith KJ, Niranjan A, Sekula RF, Lunsford LD
Institution:Marion Bloch Neuroscience Institute, Saint Luke's Hospital, Kansas City, Missouri, USA. Electronic address: Pennsylvania, USA. Pennsylvania, USA. Pennsylvania, USA. Pennsylvania, USA.
Journal:World Neurosurg. 2019 May;125:207-216. doi: 10.1016/j.wneu.2018.12.204. Epub 2019 Jan 17.

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