Trigeminal Neuralgia
August 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Trigeminal Neuralgia abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Trigeminal Neuralgia. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Trigeminal Neuralgia. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Trigeminal Neuralgia every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia.
Authors:Sandrini G, De Icco R, Tassorelli C, Smania N, Tamburin S
Institution:C. Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy. Verona, Piazzale Scuro 10, I-37134, Verona, Italy. Verona, Italy.
Journal:J Headache Pain. 2017 Dec;18(1):38. doi: 10.1186/s10194-017-0744-z. Epub 2017 Mar 21.

2:Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial.
Authors:Zakrzewska JM, Palmer J, Morisset V, Giblin GM, Obermann M, Ettlin DA, Cruccu G, Bendtsen L, Estacion M, Derjean D, Waxman SG, Layton G, Gunn K, Tate S
Institution:Facial Pain Unit, Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, University College London Hospitals NHS Foundation Trust/University College London, London, UK. Electronic address: j.zakrzewska@ucl.ac.uk. Essen, Germany; Center for Neurology, Asklepios Hospitals Schildautal, Seesen, Germany. University of Zurich, Zurich, Switzerland. University of Copenhagen, Nordre Ringvej 67, 2600 Glostrup, Denmark. Yale University School of Medicine, and Veterans Affairs Medical Center, West Haven, CT, USA. Yale University School of Medicine, and Veterans Affairs Medical Center, West Haven, CT, USA.
Journal:Lancet Neurol. 2017 Apr;16(4):291-300. doi: 10.1016/S1474-4422(17)30005-4. Epub 2017 Feb 17.

3:Trigeminal nerve block with alcohol for medically intractable classic trigeminal neuralgia: long-term clinical effectiveness on pain.
Authors:Han KR, Chae YJ, Lee JD, Kim C
Institution:Kichan Pain Clinic, Suwon, Korea.
Journal:Int J Med Sci. 2017 Jan 1;14(1):29-36. doi: 10.7150/ijms.16964. eCollection 2017.

4:Topical Review: Potential Use of Botulinum Toxin in the Management of Painful Posttraumatic Trigeminal Neuropathy.
Authors:Moreau N, Dieb W, Descroix V, Svensson P, Ernberg M, Boucher Y
Journal:J Oral Facial Pain Headache. 2017 Winter;31(1):7-18. doi: 10.11607/ofph.1753.

5:Options in treating trigeminal neuralgia: Experience with 195 patients.
Authors:Hitchon PW, Holland M, Noeller J, Smith MC, Moritani T, Jerath N, He W
Institution:Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, IA, United States. Electronic address: patrick-hitchon@uiowa.edu. City, IA, United States. City, IA, United States. Iowa City, IA, United States. City, IA, United States. City, IA, United States. Newark, NJ, United States.
Journal:Clin Neurol Neurosurg. 2016 Oct;149:166-70. doi: 10.1016/j.clineuro.2016.08.016. Epub 2016 Aug 17.

6:IMMEDIATE PAIN RELIEF BY MICROVASCULAR DECOMPRESSION FOR IDIOPATHIC TRIGEMINAL NEURALGIA.
Authors:ul Haq N, Ali M, Khan HM, Ishaq M, Khattak MI
Journal:J Ayub Med Coll Abbottabad. 2016 Jan-Mar;28(1):52-5.

7:Microvascular decompression for elderly patients with trigeminal neuralgia.
Authors:Phan K, Rao PJ, Dexter M
Institution:Department of Neurosurgery, Westmead Hospital, Hawkesbury Road, Westmead, NSW 2145, Australia; Faculty of Medicine, University of Sydney, Sydney, NSW, Australia. Electronic address: kphan.vc@gmail.com. 2145, Australia; Department of Surgery, University of New South Wales, Sydney, NSW, Australia. 2145, Australia; Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.
Journal:J Clin Neurosci. 2016 Jul;29:7-14. doi: 10.1016/j.jocn.2015.11.027. Epub 2016 Mar 2.

8:Trigeminal neuralgia (part II): Factors affecting early pharmacotherapeutic outcome.
Authors:Benoliel R, Zini A, Khan J, Almoznino G, Sharav Y, Haviv Y
Institution:Rutgers School of Dental Medicine, Rutgers State University of New Jersey, USA rafael.benoliel@rutgers.edu. University-Hadassah, Israel. University-Hadassah, Israel Department of Oral Medicine, Oral and Maxillofacial Center, Medical Corps, Israel Defense Forces, Israel. University-Hadassah, Israel. University-Hadassah, Israel.
Journal:Cephalalgia. 2016 Jul;36(8):747-59. doi: 10.1177/0333102415611406. Epub 2015 Oct 9.

9:Repeat Gamma-Knife Radiosurgery for Refractory or Recurrent Trigeminal Neuralgia with Consideration About the Optimal Second Dose.
Authors:Park SC, Kwon do H, Lee do H, Lee JK
Institution:Department of Neurosurgery, Asan Medical Center, Seoul, Korea.; Department of Neurosurgery, Asan Medical Center, Seoul, Korea; Department of Neurosurgery, College of Medicine, University of Ulsan, Seoul, Korea. Electronic address: jklee2@icloud.com.
Journal:World Neurosurg. 2016 Feb;86:371-83. doi: 10.1016/j.wneu.2015.08.056. Epub 2015 Sep 2.

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