Ductal Carcinoma in Situ of the Breast
January 2019 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Ductal Carcinoma in Situ of the Breast. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Ductal Carcinoma in Situ of the Breast. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Ductal Carcinoma In Situ.
Authors:Fu F, Gilmore RC, Jacobs LK
Institution:Fujian Medical University Union Hospital, 29 Xinquan Rd, DongJieKou SangQuan, Gulou Qu, Fuzhou Shi, Fujian Sheng 350001, China. Orleans Street, Baltimore, MD 21287, USA. Orleans Street, Baltimore, MD 21287, USA. Electronic address: Ljacob14@jhmi.edu.
Journal:Surg Clin North Am. 2018 Aug;98(4):725-745. doi: 10.1016/j.suc.2018.03.007. Epub 2018 May 28.

2:Factors associated with the increasing trend of contralateral prophylactic mastectomy among patients with ductal carcinoma in situ: Analysis of Surveillance, Epidemiology, and End Results data.
Authors:You Q, Chen K, Li Y, Lai J, Fang Y, Shen S, Liu Y, Su F, Yu F
Institution:Breast Tumor Center, Sun Yat-Sen MemorialHospital, SunYat-Sen University, 107 Yanjiang West Road, Guangzhou, 510120, China; Guangdong Provincial Key Laboratory of Malignant TumorEpigenetics and Gene Regulation, Sun Yat-Sen MemorialHospital, SunYat-Sen University, Guangzhou, 510120, China. Electronic address: fengxisu@vip.163.com.; Breast Tumor Center, Sun Yat-Sen MemorialHospital, SunYat-Sen University, 107 Yanjiang West Road, Guangzhou, 510120, China; Guangdong Provincial Key Laboratory of Malignant TumorEpigenetics and Gene Regulation, Sun Yat-Sen MemorialHospital, SunYat-Sen University, Guangzhou, 510120, China. Electronic address: yufengy@mail.sysu.edu.cn.
Journal:Breast. 2018 Aug;40:147-155. doi: 10.1016/j.breast.2018.05.001. Epub 2018 May 22.

3:Ductal carcinoma in-situ arising within benign phyllodes tumours.
Authors:Lui SA, Oh HB, Wang S, Chan CW
Institution:Division of Breast Surgery, Department of Surgery, National University Health System , Singapore. System , Singapore. System , Singapore. System , Singapore.
Journal:Ann R Coll Surg Engl. 2018 Apr;100(4):e97-e102. doi: 10.1308/rcsann.2018.0024. Epub 2018 Feb 27.

4:Controversies Regarding the Diagnosis and Management of Ductal Carcinoma In Situ.
Authors:Levinsohn E, Altman M, Chagpar AB
Journal:Am Surg. 2018 Jan 1;84(1):1-6.

5:Is DCIS Overrated?
Authors:Feinberg J, Wetstone R, Greenstein D, Borgen P
Institution:Department of Surgery, Maimonides Breast Center, Maimonides Medical Center, Research Fellow, Oxford University, Oxford, England. PBorgen@maimonidesmed.org.
Journal:Cancer Treat Res. 2018;173:53-72. doi: 10.1007/978-3-319-70197-4_5.

6:Hypofractionated volumetric modulated arc therapy in ductal carcinoma in situ: toxicity and cosmetic outcome from a prospective series.
Authors:De Rose F, Fogliata A, Franceschini D, Iftode C, Torrisi R, Masci G, Sagona A, Tinterri C, Testori A, Gatzemeier W, Fernandes B, Rahal D, Cozzi L, Santoro A, Scorsetti M
Institution:1 Department of Radiotherapy and Radiosurgery, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 2 Department of Medical Oncology, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 3 Department of Breast Surgery, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 4 Department of Pathology, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 5 Department of Biomedical Sciences, Humanitas University , Milan, Rozzano , Italy.
Journal:Br J Radiol. 2018 May;91(1085):20170634. doi: 10.1259/bjr.20170634. Epub 2018 Mar 20.

7:Are There Alternative Strategies for the Local Management of Ductal Carcinoma in Situ?
Authors:Rosso KJ, Weiss A, Thompson AM
Institution:Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, FCT7.6092, Unit 1434, 1400 Pressler Street, Houston, Texas 77030-4008, USA. Electronic address: AThompson1@mdanderson.org.
Journal:Surg Oncol Clin N Am. 2018 Jan;27(1):69-80. doi: 10.1016/j.soc.2017.08.002.

8:When Does Atypical Ductal Hyperplasia Require Surgical Excision?
Authors:Racz JM, Degnim AC
Institution:Department of Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. 55905, USA. Electronic address: degnim.amy@mayo.edu.
Journal:Surg Oncol Clin N Am. 2018 Jan;27(1):23-32. doi: 10.1016/j.soc.2017.07.011.

9:Impact of microinvasion on breast cancer mortality in women with ductal carcinoma in situ.
Authors:Sopik V, Sun P, Narod SA
Institution:Women's College Research Institute, 76 Grenville Street, Toronto, ON, M5S 1B1, Canada. Canada. Canada. steven.narod@wchospital.ca. steven.narod@wchospital.ca.
Journal:Breast Cancer Res Treat. 2018 Feb;167(3):787-795. doi: 10.1007/s10549-017-4572-2. Epub 2017 Nov 8.

10:Detection Rates of Ductal Carcinoma in Situ with Biennial Digital Mammography Screening: Radiologic Findings Support Pathologic Model of Tumor Progression.
Authors:Weigel S, Khil L, Hense HW, Decker T, Wellmann J, Heidrich J, Sommer A, Heidinger O, Heindel W
Institution:From the Institute of Clinical Radiology and Reference Center for Mammography (S.W., T.D., A.S., W.H.) and Institute of Epidemiology and Social Medicine (H.W.H., J.W.), University of Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany; Cancer Registry of North Rhine-Westphalia, Muenster, Germany (L.K., H.W.H., J.H., O.H.); and Institute of Surgical Pathology, Dietrich Bonhoeffer-Klinikum, Neubrandenburg, Germany (T.D.).
Journal:Radiology. 2018 Feb;286(2):424-432. doi: 10.1148/radiol.2017170673. Epub 2017 Nov 6.

11:Modern Approaches to the Surgical Management of Malignant Breast Disease: The Role of Breast Conservation, Complete Mastectomy, Skin- and Nipple-Sparing Mastectomy.
Authors:Cil TD, McCready D
Institution:Department of Surgery, University of Toronto, Women's College Hospital, Room 8331, 76 Grenville Street, Toronto, Ontario M5S 1B2, Canada. Electronic address: tulin.cil@wchospital.ca. University Health Network, Room 3-130, 610 University Avenue, Toronto, Ontario M5G2M9, Canada.
Journal:Clin Plast Surg. 2018 Jan;45(1):1-11. doi: 10.1016/j.cps.2017.07.002. Epub 2017 Oct 5.

12:Clinical risk score to predict likelihood of recurrence after ductal carcinoma in situ treated with breast-conserving surgery.
Authors:Punglia RS, Jiang W, Lipsitz SR, Hughes ME, Schnitt SJ, Hassett MJ, Nekhlyudov L, Achacoso N, Edge S, Javid SH, Niland JC, Theriault RL, Wong YN, Habel LA
Institution:Department of Radiation Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02115, USA. rpunglia@lroc.harvard.edu. Hospital, Boston, MA, USA. Hospital, Boston, MA, USA. Outcomes and Policy Research, Dana-Farber Cancer Institute, Boston, MA, USA. Outcomes and Policy Research, Dana-Farber Cancer Institute, Boston, MA, USA. Boston, MA, USA. Buffalo, NY, USA. Washington School of Medicine, Seattle, WA, USA. Cancer Center, Duarte, CA, USA. Cancer Center, Houston, TX, USA. Stanford, CA, USA.
Journal:Breast Cancer Res Treat. 2018 Feb;167(3):751-759. doi: 10.1007/s10549-017-4553-5. Epub 2017 Oct 28.

13:Optimal Duration of Extended Adjuvant Endocrine Therapy for Early Breast Cancer; Results of the IDEAL Trial (BOOG 2006-05).
Authors:Blok EJ, Kroep JR, Meershoek-Klein Kranenbarg E, Duijm-de Carpentier M, Putter H, van den Bosch J, Maartense E, van Leeuwen-Stok AE, Liefers GJ, Nortier JWR, Rutgers EJT, van de Velde CJH
Institution:Departments of Surgery, Medical Oncology, and Medical Statistics, Leiden University Medical Center, Leiden, Netherlands; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands; Department of Internal Medicine, Reinier de Graaff Hospital, Delft, the Netherlands; Dutch Breast Cancer Research Group, Amsterdam, the Netherlands; Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Journal:J Natl Cancer Inst. 2018 Jan 1;110(1). pii: 4093022. doi: 10.1093/jnci/djx134.

14:Severe depression more common in patients with ductal carcinoma in situ than early-stage invasive breast cancer patients.
Authors:Gregorowitsch ML, van den Bongard HJGD, Young-Afat DA, Pignol JP, van Gils CH, May AM, Verkooijen HM
Institution:Department of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. m.l.gregorowitsch@umcutrecht.nl.; Department of Clinical Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.; Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.
Journal:Breast Cancer Res Treat. 2018 Jan;167(1):205-213. doi: 10.1007/s10549-017-4495-y. Epub 2017 Sep 11.

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