Ductal Carcinoma in Situ of the Breast
September 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Ductal Carcinoma in Situ of the Breast. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Ductal Carcinoma in Situ of the Breast. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Triple-negative and HER2 positive ductal carcinoma in situ of the breast: characteristics, behavior, and biomarker profile.
Authors:Takahashi S, Thike AA, Koh VCY, Sasano H, Tan PH
Institution:Department of Pathology, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan. Academia, Diagnostics Tower, Singapore, 169856, Singapore. Academia, Diagnostics Tower, Singapore, 169856, Singapore. Academia, Diagnostics Tower, Singapore, 169856, Singapore. Miyagi, 980-8575, Japan. Sendai, Miyagi, 980-8574, Japan. Academia, Diagnostics Tower, Singapore, 169856, Singapore. tan.puay.hoon@singhealth.com.sg. tan.puay.hoon@singhealth.com.sg. Diagnostics Tower, Singapore, 169856, Singapore. tan.puay.hoon@singhealth.com.sg. Singapore, 14 Medical Drive, MD6, #14-02T, Singapore, 117599, Singapore. tan.puay.hoon@singhealth.com.sg.
Journal:Virchows Arch. 2018 Sep;473(3):275-283. doi: 10.1007/s00428-018-2416-z. Epub 2018 Jul 23.

2:Ductal Carcinoma In Situ.
Authors:Fu F, Gilmore RC, Jacobs LK
Institution:Fujian Medical University Union Hospital, 29 Xinquan Rd, DongJieKou SangQuan, Gulou Qu, Fuzhou Shi, Fujian Sheng 350001, China. Orleans Street, Baltimore, MD 21287, USA. Orleans Street, Baltimore, MD 21287, USA. Electronic address: Ljacob14@jhmi.edu.
Journal:Surg Clin North Am. 2018 Aug;98(4):725-745. doi: 10.1016/j.suc.2018.03.007. Epub 2018 May 28.

3:Use of Breast Magnetic Resonance Imaging in Women Diagnosed With Atypical Ductal Hyperplasia at Core Needle Biopsy Helps Select Women for Surgical Excision.
Authors:Amitai Y, Menes T, Golan O
Institution:Department of Radiology, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: yoavslava@yahoo.com. Medicine, Tel Aviv University, Tel Aviv, Israel. Medicine, Tel Aviv University, Tel Aviv, Israel.
Journal:Can Assoc Radiol J. 2018 Aug;69(3):240-247. doi: 10.1016/j.carj.2018.03.003. Epub 2018 Jun 27.

4:Oncoplastic breast surgery for the management of ductal carcinoma in situ (DCIS): is it oncologically safe? A retrospective cohort analysis.
Authors:De Lorenzi F, Di Bella J, Maisonneuve P, Rotmensz N, Corso G, Orecchia R, Colleoni M, Mazzarol G, Rietjens M, Loschi P, Marcelli S, Veronesi P, Galimberti V
Institution:Department of Plastic and Reconstructive Surgery, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy. Electronic address: francesca.delorenzi@ieo.it. Via Ripamonti 435, 20141, Milan, Italy. Ripamonti 435, 20141, Milan, Italy. Ripamonti 435, 20141, Milan, Italy. Milan, Italy. 20141, Milan, Italy. Milan, Italy. Via Ripamonti 435, 20141, Milan, Italy. Via Ripamonti 435, 20141, Milan, Italy. Via Ripamonti 435, 20141, Milan, Italy. piazza Edmondo Malan 1, San Donato Milanese, 20097, Milan, Italy. Milan, Italy. Milan, Italy.
Journal:Eur J Surg Oncol. 2018 Jul;44(7):957-962. doi: 10.1016/j.ejso.2018.04.015. Epub 2018 Apr 24.

5:Controversies Regarding the Diagnosis and Management of Ductal Carcinoma In Situ.
Authors:Levinsohn E, Altman M, Chagpar AB
Journal:Am Surg. 2018 Jan 1;84(1):1-6.

6:Role of postoperative radiotherapy in reducing ipsilateral recurrence in DCIS: an observational study of 1048 cases.
Authors:Corradini S, Pazos M, Schonecker S, Reitz D, Niyazi M, Ganswindt U, Schrodi S, Braun M, Polcher M, Mahner S, Harbeck N, Engel J, Belka C
Institution:Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany. Stefanie.corradini@med.uni-muenchen.de.; Department of Therapeutic Radiology and Oncology, Innsbruck Medical University, Innsbruck, Austria.; Munich Cancer Registry (MCR) of the Munich Tumour Centre (TZM) at the Institute of Medical Information Processing, Biometry and Epidemiology (IBE), University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.; Red Cross Breast Centre, Taxisstr. 3, 80637, Munich, Germany.; Department of Gynecology and Obstetrics, Breast Centre, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Journal:Radiat Oncol. 2018 Feb 9;13(1):25. doi: 10.1186/s13014-018-0964-7.

7:Is DCIS Overrated?
Authors:Feinberg J, Wetstone R, Greenstein D, Borgen P
Institution:Department of Surgery, Maimonides Breast Center, Maimonides Medical Center, Research Fellow, Oxford University, Oxford, England. PBorgen@maimonidesmed.org.
Journal:Cancer Treat Res. 2018;173:53-72. doi: 10.1007/978-3-319-70197-4_5.

8:Hypofractionated volumetric modulated arc therapy in ductal carcinoma in situ: toxicity and cosmetic outcome from a prospective series.
Authors:De Rose F, Fogliata A, Franceschini D, Iftode C, Torrisi R, Masci G, Sagona A, Tinterri C, Testori A, Gatzemeier W, Fernandes B, Rahal D, Cozzi L, Santoro A, Scorsetti M
Institution:1 Department of Radiotherapy and Radiosurgery, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 2 Department of Medical Oncology, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 3 Department of Breast Surgery, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 4 Department of Pathology, Humanitas Research Hospital and Cancer Center , Milan, Rozzano , Italy.; 5 Department of Biomedical Sciences, Humanitas University , Milan, Rozzano , Italy.
Journal:Br J Radiol. 2018 May;91(1085):20170634. doi: 10.1259/bjr.20170634. Epub 2018 Mar 20.

9:Are There Alternative Strategies for the Local Management of Ductal Carcinoma in Situ?
Authors:Rosso KJ, Weiss A, Thompson AM
Institution:Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, FCT7.6092, Unit 1434, 1400 Pressler Street, Houston, Texas 77030-4008, USA. Electronic address: AThompson1@mdanderson.org.
Journal:Surg Oncol Clin N Am. 2018 Jan;27(1):69-80. doi: 10.1016/j.soc.2017.08.002.

10:When Does Atypical Ductal Hyperplasia Require Surgical Excision?
Authors:Racz JM, Degnim AC
Institution:Department of Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. 55905, USA. Electronic address: degnim.amy@mayo.edu.
Journal:Surg Oncol Clin N Am. 2018 Jan;27(1):23-32. doi: 10.1016/j.soc.2017.07.011.

11:Detection Rates of Ductal Carcinoma in Situ with Biennial Digital Mammography Screening: Radiologic Findings Support Pathologic Model of Tumor Progression.
Authors:Weigel S, Khil L, Hense HW, Decker T, Wellmann J, Heidrich J, Sommer A, Heidinger O, Heindel W
Institution:From the Institute of Clinical Radiology and Reference Center for Mammography (S.W., T.D., A.S., W.H.) and Institute of Epidemiology and Social Medicine (H.W.H., J.W.), University of Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany; Cancer Registry of North Rhine-Westphalia, Muenster, Germany (L.K., H.W.H., J.H., O.H.); and Institute of Surgical Pathology, Dietrich Bonhoeffer-Klinikum, Neubrandenburg, Germany (T.D.).
Journal:Radiology. 2018 Feb;286(2):424-432. doi: 10.1148/radiol.2017170673. Epub 2017 Nov 6.

12:Atypical ductal hyperplasia: Our experience in the management and long term clinical follow-up in 71 patients.
Authors:Latronico A, Nicosia L, Faggian A, Abbate F, Penco S, Bozzini A, Cannataci C, Mazzarol G, Cassano E
Institution:European Institute of Oncology, Breast Imaging Unit, Via G. Ripamonti, 435, 20141, Milano, Italy. Festa del Perdono 7, Milan, Italy. Electronic address: lucanicosia88@gmail.com. Italy. 20141, Milano, Italy. 20141, Milano, Italy. 20141, Milano, Italy. Malta. 20141, Milano, Italy. 20141, Milano, Italy.
Journal:Breast. 2018 Feb;37:1-5. doi: 10.1016/j.breast.2017.10.003. Epub 2017 Oct 12.

13:Optimal Duration of Extended Adjuvant Endocrine Therapy for Early Breast Cancer; Results of the IDEAL Trial (BOOG 2006-05).
Authors:Blok EJ, Kroep JR, Meershoek-Klein Kranenbarg E, Duijm-de Carpentier M, Putter H, van den Bosch J, Maartense E, van Leeuwen-Stok AE, Liefers GJ, Nortier JWR, Rutgers EJT, van de Velde CJH
Institution:Departments of Surgery, Medical Oncology, and Medical Statistics, Leiden University Medical Center, Leiden, Netherlands; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands; Department of Internal Medicine, Reinier de Graaff Hospital, Delft, the Netherlands; Dutch Breast Cancer Research Group, Amsterdam, the Netherlands; Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Journal:J Natl Cancer Inst. 2018 Jan 1;110(1). pii: 4093022. doi: 10.1093/jnci/djx134.

14:Carcinoma in situ of the breast in New South Wales, Australia: Current status and trends over the last 40 year.
Authors:Jacklyn G, Morrell S, McGeechan K, Houssami N, Irwig L, Pathmanathan N, Barratt A
Institution:Wiser Healthcare, Sydney School of Public Health, The University of Sydney, NSW, 2006, Australia. Electronic address: gemma.jacklyn@sydney.edu.au. of New South Wales, Sydney, NSW, 2052, Australia. Australia; Westmead Breast Cancer Institute, Westmead Hospital, Westmead, NSW, Australia. 2006, Australia.
Journal:Breast. 2018 Feb;37:170-178. doi: 10.1016/j.breast.2017.08.005. Epub 2017 Sep 5.

15:Omitting radiation therapy after lumpectomy for pure DCIS does not reduce the risk of salvage mastectomy.
Authors:Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Gu S, Fong C, Tuck A, Youngson B, Miller N, Done SJ, Chang MC, Sengupta S, Elavathil L, Jani PA, Bonin M, Lalani N, Paszat L
Institution:Department of Radiation Oncology, Toronto, ON, Canada; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. Electronic address: eileen.rakovitch@sunnybrook.ca.; Department of Pathology, Toronto, ON, Canada.; Department of Pathology, Toronto, ON, Canada; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.; Department of Pathology, London Health Sciences Centre, Toronto, ON, Canada.
Journal:Breast. 2018 Feb;37:181-186. doi: 10.1016/j.breast.2017.07.002. Epub 2017 Aug 3.

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