Sjogren's Syndrome
January 2019 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Sjogren's Syndrome abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Sjogren's Syndrome. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Sjogren's Syndrome. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Sjogren's Syndrome every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Association between Helicobacter pylori infection and Sjogren syndrome: A meta-analysis.
Authors:Chen Q, Zhou X, Tan W, Zhang M
Institution:First Clinical Medical College of Nanjing Medical University. University, Nanjing, China.
Journal:Medicine (Baltimore). 2018 Dec;97(49):e13528. doi: 10.1097/MD.0000000000013528.

2:Primary Sjogren's syndrome.
Authors:Bowman SJ
Institution:Rheumatology Department, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.
Journal:Lupus. 2018 Oct;27(1_suppl):32-35. doi: 10.1177/0961203318801673.

3:Severe, life-threatening phenotype of primary Sjogren's syndrome: clinical characterisation and outcomes in 1580 patients (GEAS-SS Registry).
Authors:Flores-Chavez A, Kostov B, Solans R, Fraile G, Maure B, Feijoo-Masso C, Rascon FJ, Perez-Alvarez R, Zamora-Pasadas M, Garcia-Perez A, Lopez-Dupla M, Duarte-Millan MA, Ripoll M, Fonseca-Aizpuru E, Guisado-Vasco P, Pinilla B, de-la-Red G, Chamorro AJ, Morcillo C, Fanlo P, Soto-Cardenas MJ, Retamozo S, Ramos-Casals M, Brito-Zeron P
Institution:Lab. Autoimmune Dis. Josep Font, IDIBAPS, ICMiD, Hosp. Clinic, Barcelona; Biomedical Res. Unit 02, Clin.Epidemiol.Res. Unit, UMAE, Specialties Hosp., Western Med. Center, Mexican Inst.for Social Security, Guadalajara; & Univ. of Colima, Mexico.; Primary Care Research Group, IDIBAPS, Centre d'Assistencia Primaria ABS Les Corts, GESCLINIC, Barcelona, Spain.; Systemic Autoimmune Diseases Unit, Hospital Vall d'Hebron, Barcelona, Spain.; Systemic Autoimmune Diseases Unit, Hospital Ramon y Cajal, Madrid, Spain.; Systemic Autoimmune Diseases Unit, Complejo Hospitalario Universitario, Vigo, Spain.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):121-129. Epub 2018 Aug 14.

4:One year in review 2018: Sjogren's syndrome.
Authors:Argyropoulou OD, Valentini E, Ferro F, Leone MC, Cafaro G, Bartoloni E, Baldini C
Institution:Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece. of Pisa, Italy. of Pisa, Italy.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):14-26. Epub 2018 Jul 18.

5:Clinical and immunological parameters of Sjogren's syndrome.
Authors:Psianou K, Panagoulias I, Papanastasiou AD, de Lastic AL, Rodi M, Spantidea PI, Degn SE, Georgiou P, Mouzaki A
Institution:Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, Patras, Greece. University of Patras, Patras, Greece. University of Patras, Patras, Greece. University of Patras, Patras, Greece. University of Patras, Patras, Greece. Greece. University of Patras, Patras, Greece. Electronic address: mouzaki@upatras.gr.
Journal:Autoimmun Rev. 2018 Oct;17(10):1053-1064. doi: 10.1016/j.autrev.2018.05.005. Epub 2018 Aug 10.

6:Customary practices in the monitoring of dry eye disease in Sjogren's syndrome.
Authors:Acs M, Caffery B, Barnett M, Edmonds C, Johnson-Tong L, Maharaj R, Pemberton B, Papinski D, Harthan J, Srinivasan S
Institution:Toronto Eye Care, 55 Bloor Street West, Toronto, ON, Canada. Electronic address: miraacs@hotmail.com. Suite 406, Brampton, ON, Canada. of Waterloo, 200 University Avenue West, Waterloo, ON, Canada. Michigan Avenue, Chicago, IL, USA. of Waterloo, 200 University Avenue West, Waterloo, ON, Canada.
Journal:J Optom. 2018 Oct - Dec;11(4):232-241. doi: 10.1016/j.optom.2018.05.001. Epub 2018 Jul 17.

7:Update on Sjogren Syndrome and Other Causes of Sicca in Older Adults.
Authors:Baer AN, Walitt B
Institution:Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 4000, Mason Lord Center Tower, Baltimore, MD 21224, USA; National Institute of Dental and Craniofacial Research, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address: alanbaer@jhmi.edu.
Journal:Rheum Dis Clin North Am. 2018 Aug;44(3):419-436. doi: 10.1016/j.rdc.2018.03.002.

8:The prevalence and relevance of traditional cardiovascular risk factors in primary Sjogren's syndrome.
Authors:Bartoloni E, Alunno A, Valentini V, Valentini E, La Paglia GMC, Leone MC, Cafaro G, Marcucci E, Bonifacio AF, Luccioli F, Gerli R
Institution:Rheumatology Unit, University of Perugia, Italy.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):113-120. Epub 2018 May 30.

9:Prevalence and spectrum of symptomatic pulmonary involvement in primary Sjogren's syndrome.
Authors:Kampolis CF, Fragkioudaki S, Mavragani CP, Zormpala A, Samakovli A, Moutsopoulos HM
Institution:Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece. chkamp77@gmail.com. University of Athens, Greece. National and Kapodistrian University of Athens, Greece. University of Athens, Greece.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):94-101. Epub 2018 May 29.

10:Advances in the diagnosis and treatment of Sjogren's syndrome.
Authors:Chen X, Wu H, Wei W
Institution:Institute of Clinical Pharmacology, Anhui Medical University, Hefei,, 230032, Anhui, China. Hefei, 230032, Anhui, China. Hefei, 230032, Anhui, China. Anhui, China. wuhuaxun@ahmu.edu.cn. Hefei, 230032, Anhui, China. wuhuaxun@ahmu.edu.cn. Hefei, 230032, Anhui, China. wuhuaxun@ahmu.edu.cn. Anhui, China. wwei@ahmu.edu.cn. Hefei, 230032, Anhui, China. wwei@ahmu.edu.cn. Hefei, 230032, Anhui, China. wwei@ahmu.edu.cn.
Journal:Clin Rheumatol. 2018 Jul;37(7):1743-1749. doi: 10.1007/s10067-018-4153-8. Epub 2018 May 26.

11:Do antimalarials protect against damage accrual in primary Sjogren's syndrome? Results from a Latin-American retrospective cohort.
Authors:Hernandez-Molina G, Valim V, Secco A, Atisha-Fregoso Y, Guerra E, Adrover M, Lage Santos AJ, Catalan-Pellet A
Institution:Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Subiran, Mexico City, Mexico.; Department of Rheumatology, Hospital Universitario Cassiano Antonio de Moraes, Universidade Federal do Espirito Santo, Brazil.; Department of Rheumatology, Hospital Bernardino Rivadavia, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina. acapellet@gmail.com.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):182-185. Epub 2018 Apr 19.

12:Acute fibrinous and organizing pneumonia as initial presentation of primary Sjogren's syndrome: a case report and literature review.
Authors:Wang Y, Zhao S, Du G, Ma S, Lin Q, Lin J, Zheng K, Zhang G, Matucci-Cerinic M
Institution:Department of Rheumatology and Immunology, Shantou Central Hospital, Shantou, Guangdong, China. stzxyywyk@126.com. Medicine, Division of Rheumatology, AOUC, University of Florence, Florence, Italy. stzxyywyk@126.com. China. China. Guangdong, China. Guangdong, China. Guangdong, China. China. Medicine, Division of Rheumatology, AOUC, University of Florence, Florence, Italy.
Journal:Clin Rheumatol. 2018 Jul;37(7):2001-2005. doi: 10.1007/s10067-018-4128-9. Epub 2018 May 2.

13:Characteristics and risk factors of pulmonary arterial hypertension in patients with primary Sjogren's syndrome.
Authors:Yan S, Li M, Wang H, Yang X, Zhao J, Wang Q, Liu Y, Lai J, Tian Z, Song H, Zhao Y, Zeng X
Institution:Department of Rheumatology, Beijing Jishuitan Hospital, Beijing, China.; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Journal:Int J Rheum Dis. 2018 May;21(5):1068-1075. doi: 10.1111/1756-185X.13290. Epub 2018 Apr 6.

14:Association between primary Sjogren's syndrome, cardiovascular and cerebrovascular disease: a systematic review and meta-analysis.
Authors:Yong WC, Sanguankeo A, Upala S
Institution:Department of Internal Medicine, Greenfield Family Medicine, Baystate Franklin Medical Center, Greenfield, MA, USA. MD, USA; and Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. asangua1@jhmi.edu. University of Chicago, USA; and Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):190-197. Epub 2018 Mar 19.

15:Factors associated with severe dry eye in primary Sjogren's syndrome diagnosed patients.
Authors:Fernandez Castro M, Sanchez-Piedra C, Andreu JL, Martinez Taboada V, Olive A, Rosas J
Institution:Rheumatology, Hospital Universitario Infanta Sofia, Avenida de Europa 34, 28703, San Sebastian de los Reyes, Madrid, Spain. monfercas@yahoo.es.
Journal:Rheumatol Int. 2018 Jun;38(6):1075-1082. doi: 10.1007/s00296-018-4013-5. Epub 2018 Mar 20.

16:Cardiovascular Disease in Primary Sjogren's Syndrome.
Authors:Berardicurti O, Ruscitti P, Cipriani P, Ciccia F, Liakouli V, Guggino G, Carubbi F, Di Benedetto P, Triolo G, Giacomelli R
Institution:Division of Rheumatology, University of L`Aquila, L`Aquila, Italy.
Journal:Rev Recent Clin Trials. 2018;13(3):164-169. doi: 10.2174/1574887113666180315130336.

17:The prognosis of pulmonary arterial hypertension associated with primary Sjogren's syndrome: a cohort study.
Authors:Liu Z, Yang X, Tian Z, Qian J, Wang Q, Zhao J, Huang C, Liu Y, Guo X, Wang H, Lai J, Li M, Zhao Y, Zeng X
Institution:1 Department of Rheumatology, Peking Union Medical College Hospital, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.; 2 Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Journal:Lupus. 2018 Jun;27(7):1072-1080. doi: 10.1177/0961203318756287. Epub 2018 Feb 8.

18:Clinical practice guideline for Sjogren's syndrome 2017.
Authors:Sumida T, Azuma N, Moriyama M, Takahashi H, Asashima H, Honda F, Abe S, Ono Y, Hirota T, Hirata S, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Sano H, Ogawa Y, Tsubota K, Ryo K, Saito I, Tanaka A, Nakamura S, Takamura E, Tanaka M, Suzuki K, Takeuchi T, Yamakawa N, Mimori T, Ohta A, Nishiyama S, Yoshihara T, Suzuki Y, Kawano M, Tomiita M, Tsuboi H
Institution:a Department of Internal Medicine , University of Tsukuba , Ibaraki , Japan.; b Clinical Practice Guideline Committee for Sjogren's Syndrome, The Research Team for Autoimmune Diseases, The Research Program for Intractable Disease of the Ministry of Health, Labor and Welfare (MHLW) , Tokyo , Japan.; c Division of Rheumatology, Department of Internal Medicine , Hyogo College of Medicine , Hyogo , Japan.; d Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences , Kyushu University , Fukuoka , Japan.; e The First Department of Internal Medicine , School of Medicine, University of Occupational and Environmental Health, Japan , Fukuoka , Japan.
Journal:Mod Rheumatol. 2018 May;28(3):383-408. doi: 10.1080/14397595.2018.1438093. Epub 2018 Mar 13.

19:Increased risk of coronary heart disease among patients with primary Sjogren's syndrome: a nationwide population-based cohort study.
Authors:Wu XF, Huang JY, Chiou JY, Chen HH, Wei JC, Dong LL
Institution:Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Taiwan. Taiwan. jccwei@gmail.com. jccwei@gmail.com. Taiwan. jccwei@gmail.com. College, Huazhong University of Science and Technology, Wuhan, Hubei, China. fsmy@tjh.tjmu.edu.cn.
Journal:Sci Rep. 2018 Feb 2;8(1):2209. doi: 10.1038/s41598-018-19580-y.

20:Assessing health-related quality of life in primary Sjogren's syndrome-The PSS-QoL.
Authors:Lackner A, Stradner MH, Hermann J, Unger J, Stamm T, Graninger WB, Dejaco C
Institution:Division of Rheumatology and Immunology, Department of Internal Medicine, Medical University Graz, Auenbruggerplatz 15, 8036 Graz, Austria. University Graz, Auenbruggerplatz 15, 8036 Graz, Austria. Electronic address: martin.stradner@medunigraz.at. University Graz, Auenbruggerplatz 15, 8036 Graz, Austria. University Graz, Auenbruggerplatz 15, 8036 Graz, Austria; Department of Health Studies, Institute of Occupational Therapy, University of Applied Sciences JOANNEUM, Kaiser-Franz-Josef Strasse 24, 8344 Bad Gleichenberg, Austria. Vienna, Austria. University Graz, Auenbruggerplatz 15, 8036 Graz, Austria. University Graz, Auenbruggerplatz 15, 8036 Graz, Austria; Rheumatology Service, South Tyrolean Health Trust, Hospital of Bruneck, Spitalstrasse 11, 39031 Bruneck, Italy.
Journal:Semin Arthritis Rheum. 2018 Aug;48(1):105-110. doi: 10.1016/j.semarthrit.2017.11.007. Epub 2017 Nov 27.

21:Survey of Ophthalmologists Regarding Practice Patterns for Dry Eye and Sjogren Syndrome.
Authors:Bunya VY, Fernandez KB, Ying GS, Massaro-Giordano M, Macchi I, Sulewski ME, Hammersmith KM, Nagra PK, Rapuano CJ, Orlin SE
Institution:Department of Ophthalmology (V.Y.B., K.B.F., G.-s.Y., M.M.-G., I.M., M.E.S., S.E.O.), Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA; Department of Ophthalmology (G.-s.Y.), Center for Preventive Ophthalmology and Biostatistics, University of Pennsylvania, Philadelphia, PA; and Corneal Service (K.M.H., P.K.N., C.J.R.), Wills Eye Hospital, Philadelphia, PA.
Journal:Eye Contact Lens. 2018 Nov;44 Suppl 2:S196-S201. doi: 10.1097/ICL.0000000000000448.

22:Low-level laser therapy for xerostomia in primary Sjogren's syndrome: a randomized trial.
Authors:Fidelix T, Czapkowski A, Azjen S, Andriolo A, Neto PH, Trevisani V
Institution:Department of Evidence-Based Health, Universidade Federal de Sao Paulo (UNIFESP), Rua Barao do Triunfo, 156/232, Sao Paulo, SP, 04602-000, Brazil. fidelixtania@gmail.com.; Department of Radiology, UNIFESP, Sao Paulo, SP, Brazil.; Department of Laboratory Medicine, UNIFESP, Sao Paulo, SP, Brazil.
Journal:Clin Rheumatol. 2018 Mar;37(3):729-736. doi: 10.1007/s10067-017-3898-9. Epub 2017 Nov 9.

23:Depression in primary Sjogren's syndrome: a systematic review and meta-analysis.
Authors:Cui Y, Li L, Yin R, Zhao Q, Chen S, Zhang Q, Shen B
Institution:a Department of Nursing , The Second Affiliated Hospital of Nantong University , Nantong , China. Nantong , China.
Journal:Psychol Health Med. 2018 Feb;23(2):198-209. doi: 10.1080/13548506.2017.1339895. Epub 2017 Jun 16.

24:Use and withdrawal of immunosuppressors in primary Sjogren's syndrome.
Authors:Torres-Ruiz J, Faz-Munoz D, Hernandez-Diaz N, Hernandez-Molina G
Institution:Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico. gabyhm@yahoo.com.
Journal:Clin Exp Rheumatol. 2018 May-Jun;36 Suppl 112(3):177-181. Epub 2017 Apr 18.

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