Meniere's Disease
June 2018 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Meniere's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Meniere's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Meniere's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Meniere's Disease every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Newly Diagnosed Meniere's Disease: Clinical Course With Initiation of Noninvasive Treatment Including an Accounting of Vestibular Migraine.
Authors:Sbeih F, Christov F, Gluth MB
Institution:1 University of Central Florida College of Medicine, Orlando, Florida, USA.
Journal:Ann Otol Rhinol Laryngol. 2018 May;127(5):331-337. doi: 10.1177/0003489418763224. Epub 2018 Mar 16.

2:Meniere and Friends: Imaging and Classification of Hydropic Ear Disease.
Authors:Gurkov R
Institution:*Department of Otorhinolaryngology Head and Neck Surgery daggerGerman Centre for Vertigo and Balance Disorder, University of Munich, Munchen, Germany.
Journal:Otol Neurotol. 2017 Dec;38(10):e539-e544. doi: 10.1097/MAO.0000000000001479.

3:Is betahistine effective for Menieres disease?
Authors:Rosenbaum A, Winter M
Institution:Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, Chile. Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile. Email: Address:Centro Evidencia UC, Pontificia Universidad Catolica de Chile, Centro de Innovacion UC Anacleta Angelini, Avda. Vicuna Mackenna 4860, Macul, Santiago, Chile.
Journal:Medwave. 2017 Oct 31;17(8):e7068.

4:Mastoid and Inner Ear Measurements in Patients With Meniere's Disease.
Authors:Sugihara EM, Marinica AL, Vandjelovic ND, Kelley BM, Sana SS, Starkey NE, Babu SC
Institution:*Department of Otolaryngology-Head and Neck Surgery daggerDepartment of General Surgery, Detroit Medical Center, Michigan State University, Detroit double daggerDepartment of Radiology, Michigan State University, East Lansing section signDepartment of Otology, Neurotology, and Skull Base Surgery, Michigan Ear Institute, Farmington Hills, Michigan.
Journal:Otol Neurotol. 2017 Dec;38(10):1484-1489. doi: 10.1097/MAO.0000000000001576.

5:Stress and Unusual Events Exacerbate Symptoms in Meniere's Disease: A Longitudinal Study.
Authors:Yeo NL, White MP, Ronan N, Whinney DJ, Curnow A, Tyrrell J
Institution:European Centre for Environment and Human Health, University of Exeter Medical School, Truro Campus, Truro. School, Truro Campus, Truro. School, Truro Campus, Truro. School, Truro Campus, Truro.
Journal:Otol Neurotol. 2018 Jan;39(1):73-81. doi: 10.1097/MAO.0000000000001592.

6:MRI in otology: applications in cholesteatoma and Meniere's disease.
Authors:Lingam RK, Connor SEJ, Casselman JW, Beale T
Institution:London Northwest Healthcare NHS Trust, London, UK.
Journal:Clin Radiol. 2018 Jan;73(1):35-44. doi: 10.1016/j.crad.2017.09.002. Epub 2017 Sep 29.

7:Saccular measurements in routine MRI can predict hydrops in Meniere's disease.
Authors:Simon F, Guichard JP, Kania R, Franc J, Herman P, Hautefort C
Institution:Department of Otorhinolaryngology, AP-HP, Hopital Lariboisiere, 2 Rue Ambroise Pare, 75010, Paris, France. Paris, France. Pare, 75010, Paris, France. Paris, France. Pare, 75010, Paris, France. Pare, 75010, Paris, France.
Journal:Eur Arch Otorhinolaryngol. 2017 Dec;274(12):4113-4120. doi: 10.1007/s00405-017-4756-8. Epub 2017 Sep 26.

8:Nocebo Effect in Meniere's Disease: A Meta-analysis of Placebo-controlled Randomized Controlled Trials.
Authors:Dimitriadis PA, Zis P
Institution:*Department of Ear, Nose and Throat Surgery, Sheffield Teaching Hospitals NHS Trust daggerAcademic Department of Neurosciences, University of Sheffield, Sheffield, UK.
Journal:Otol Neurotol. 2017 Oct;38(9):1370-1375. doi: 10.1097/MAO.0000000000001555.

9:Comparative study between the caloric vestibular and the video-head impulse tests in unilateral Meniere's disease.
Authors:Cordero-Yanza JA, Arrieta Vazquez EV, Hernaiz Leonardo JC, Mancera Sanchez J, Hernandez Palestina MS, Perez-Fernandez N
Institution:a Department of Otolaryngology & Head and Neck Surgery , Instituto Nacional de Rehabilitacion , CDMX, Mexico , Mexico.; b Department of Otolaryngology , Clinica Universidad de Navarra , Pamplona , Spain.
Journal:Acta Otolaryngol. 2017 Nov;137(11):1178-1182. doi: 10.1080/00016489.2017.1354395. Epub 2017 Jul 25.

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