Meniere's Disease
June 2017 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Meniere's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Meniere's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Meniere's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Meniere's Disease every 3 months. Thank you for your ongoing subscription to this publication.

Sincerely,
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Assessment of endolymphatic hydrops and otolith function in patients with Meniere's disease.
Authors:Okumura T, Imai T, Takimoto Y, Takeda N, Kitahara T, Uno A, Kamakura T, Osaki Y, Watanabe Y, Inohara H
Institution:Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Journal:Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1413-1421. doi: 10.1007/s00405-016-4418-2. Epub 2016 Dec 10.

2:Ion transport its regulation in the endolymphatic sac: suggestions for clinical aspects of Meniere's disease.
Authors:Mori N, Miyashita T, Inamoto R, Matsubara A, Mori T, Akiyama K, Hoshikawa H
Institution:Osaka Bay Central Hospital, 1-8-30 Chikkou, Minato-ku, Osaka, 552-0021, Japan. nozomu@pe.kagawa-u.ac.jp. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan. nozomu@pe.kagawa-u.ac.jp. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan. Miki-cho, Ikenobe 1750-1, Kagawa, 761-0793, Japan.
Journal:Eur Arch Otorhinolaryngol. 2017 Apr;274(4):1813-1820. doi: 10.1007/s00405-016-4362-1. Epub 2016 Nov 1.

3:Is gentamycin delivery via sustained-release vehicles a safe and effective treatment for refractory Meniere's disease? A critical analysis of published interventional studies.
Authors:Vlastarakos PV, Iacovou E, Nikolopoulos TP
Institution:ENT Department, MITERA Infirmary, 6 Erythrou Stavrou Street, 15123, Marousi-Athens, Greece. pevlast@hotmail.com.
Journal:Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1309-1315. doi: 10.1007/s00405-016-4294-9. Epub 2016 Sep 13.

4:What is Meniere's disease? A contemporary re-evaluation of endolymphatic hydrops.
Authors:Gurkov R, Pyyko I, Zou J, Kentala E
Institution:Department of Otorhinolaryngology Head and Neck Surgery, University of Munich, Marchioninistr. 15, 81377, Munich, Germany. rguerkov@med.uni-muenchen.de. Marchioninistr. 15, 81377, Munich, Germany. of Tampere, 33520, Tampere, Finland. Haartmaninkatu 4E, 00290, Helsinki, Finland.
Journal:J Neurol. 2016 Apr;263 Suppl 1:S71-81. doi: 10.1007/s00415-015-7930-1. Epub 2016 Apr 15.

5:Identification of operculum and surgical results in endolymphatic sac drainage surgery.
Authors:Kitahara T, Yamanaka T
Institution:Department of Otolaryngology-Head and Neck Surgery, Nara Medical University, Nara, Japan. Electronic address: tkitahara@naramed-u.ac.jp. Nara, Japan.
Journal:Auris Nasus Larynx. 2017 Feb;44(1):116-118. doi: 10.1016/j.anl.2016.02.017. Epub 2016 Mar 19.

6:Meniett Therapy for Meniere's Disease: An Updated Meta-analysis.
Authors:Zhang SL, Leng Y, Liu B, Shi H, Lu M, Kong WJ
Institution:*Department of Otorhinolaryngology, Union Hospital daggerInstitute of Otorhinolaryngology, Union Hospital double daggerDepartment of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health section signKey Laboratory of Neurological Disorders of Education Ministry, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Journal:Otol Neurotol. 2016 Mar;37(3):290-8. doi: 10.1097/MAO.0000000000000957.

7:Efficacy and safety of betahistine treatment in patients with Meniere's disease: primary results of a long term, multicentre, double blind, randomised, placebo controlled, dose defining trial (BEMED trial).
Authors:Adrion C, Fischer CS, Wagner J, Gurkov R, Mansmann U, Strupp M
Institution:German Center for Vertigo and Balance Disorders, University Hospital Munich, Campus Grosshadern, Munich, Germany Institute for Medical Informatics, Biometry, and Epidemiology, University of Munich, Campus Grosshadern. Campus Grosshadern, Munich, Germany. Munich. Munich, Campus Grosshadern. Campus Grosshadern, Munich, Germany Department of Neurology, University Hospital Munich, 81377 Munich Michael.Strupp@med.uni-muenchen.de.
Journal:BMJ. 2016 Jan 21;352:h6816. doi: 10.1136/bmj.h6816.

8:Migraine features in patients with Meniere's disease.
Authors:Ghavami Y, Mahboubi H, Yau AY, Maducdoc M, Djalilian HR
Institution:Division of Otology, Neurotology, and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, Irvine, California, U.S.A.; Department of Biomedical Engineering, University of California, Irvine, Irvine, California, U.S.A.
Journal:Laryngoscope. 2016 Jan;126(1):163-8. doi: 10.1002/lary.25344. Epub 2015 Jun 24.

9:Disability perception in Meniere's disease: when, how much and why?
Authors:Soto-Varela A, Huertas-Pardo B, Gayoso-Diz P, Santos-Perez S, Sanchez-Sellero I
Institution:Division of Neurotology, Department of Otorhinolaryngology, Complexo Hospitalario Universitario de Santiago de Compostela, Travesia da Choupana, s/n, 15706, Santiago de Compostela, Spain. andres.soto@usc.es. Compostela, Santiago de Compostela, Spain. andres.soto@usc.es. Santiago de Compostela, Santiago de Compostela, Spain. (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain. Universitario de Santiago de Compostela, Travesia da Choupana, s/n, 15706, Santiago de Compostela, Spain. Compostela, Santiago de Compostela, Spain. Compostela, Santiago de Compostela, Spain.
Journal:Eur Arch Otorhinolaryngol. 2016 Apr;273(4):865-72. doi: 10.1007/s00405-015-3638-1. Epub 2015 May 1.

10:Relationship between hearing threshold at the affected and unaffected ear in unilateral Meniere's disease.
Authors:Albera R, Canale A, Cassandro C, Albera A, Sammartano AM, Dagna F
Institution:Department of Surgical Sciences, University of Torino, via Genova 3, 10100, Torino, Italy. roberto.albera@unito.it. Torino, Italy. Torino, Italy. Torino, Italy. Torino, Italy. Torino, Italy. federico.dagna@gmail.com.
Journal:Eur Arch Otorhinolaryngol. 2016 Jan;273(1):51-6. doi: 10.1007/s00405-014-3466-8. Epub 2015 Jan 1.

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